Receptors, Platelet-Derived Growth Factor
"Receptors, Platelet-Derived Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types.
MeSH Number(s)
D08.811.913.696.620.682.725.400.900
D12.776.543.750.060.625
D12.776.543.750.750.400.630
Concept/Terms
Receptors, Platelet-Derived Growth Factor- Receptors, Platelet-Derived Growth Factor
- Receptors, Platelet Derived Growth Factor
- Receptors, PDGF
- Platelet-Derived Growth Factor Receptor
- Platelet Derived Growth Factor Receptor
- Platelet-Derived Growth Factor Receptors
- Platelet Derived Growth Factor Receptors
- PDGF Receptor
- Receptor, PDGF
- PDGF Receptors
Below are MeSH descriptors whose meaning is more general than "Receptors, Platelet-Derived Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Platelet-Derived Growth Factor".
This graph shows the total number of publications written about "Receptors, Platelet-Derived Growth Factor" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Platelet-Derived Growth Factor" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 5 | 1 | 6 |
| 1994 | 6 | 3 | 9 |
| 1995 | 4 | 3 | 7 |
| 1996 | 4 | 4 | 8 |
| 1997 | 3 | 3 | 6 |
| 1998 | 2 | 4 | 6 |
| 1999 | 4 | 2 | 6 |
| 2000 | 1 | 2 | 3 |
| 2001 | 1 | 4 | 5 |
| 2002 | 0 | 3 | 3 |
| 2003 | 1 | 4 | 5 |
| 2004 | 3 | 2 | 5 |
| 2005 | 2 | 0 | 2 |
| 2006 | 2 | 2 | 4 |
| 2007 | 2 | 2 | 4 |
| 2008 | 3 | 3 | 6 |
| 2009 | 0 | 4 | 4 |
| 2010 | 1 | 3 | 4 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 2 | 3 |
| 2018 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, Platelet-Derived Growth Factor" by people in Profiles.
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Platelet-derived growth factor (PDGF) cross-signaling via non-corresponding receptors indicates bypassed signaling in colorectal cancer. Oncotarget. 2022 10 19; 13:1140-1152.
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A proteogenomic portrait of lung squamous cell carcinoma. Cell. 2021 08 05; 184(16):4348-4371.e40.
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ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer. Proc Natl Acad Sci U S A. 2019 08 27; 116(35):17450-17459.
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Differential prognostic impact of platelet-derived growth factor receptor expression in NSCLC. Sci Rep. 2019 07 15; 9(1):10163.
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The Long Noncoding RNA LnRPT Puts the Brakes on Pulmonary Artery Smooth Muscle Cell Proliferation. Am J Respir Cell Mol Biol. 2018 02; 58(2):138-139.
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mTOR, VEGF, PDGFR, and c-kit signaling pathway activation in Kaposi sarcoma. Hum Pathol. 2017 07; 65:157-165.
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Ponatinib promotes a G1 cell-cycle arrest of merlin/NF2-deficient human schwann cells. Oncotarget. 2017 May 09; 8(19):31666-31681.
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Target and Agent Prioritization for the Children's Oncology Group-National Cancer Institute Pediatric MATCH Trial. J Natl Cancer Inst. 2017 05 01; 109(5).
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Receptor Tyrosine Kinases: Translocation Partners in Hematopoietic Disorders. Trends Mol Med. 2017 01; 23(1):59-79.
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Human airway smooth muscle cell proliferation from asthmatics is negatively regulated by semaphorin3A. Oncotarget. 2016 Dec 06; 7(49):80238-80251.