Receptors, Metabotropic Glutamate
"Receptors, Metabotropic Glutamate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind glutamate and act through G-proteins to influence second messenger systems. Several types of metabotropic glutamate receptors have been cloned. They differ in pharmacology, distribution, and mechanisms of action.
MeSH Number(s)
D12.776.543.750.100.450
D12.776.543.750.720.200.450.500
Concept/Terms
Receptors, Metabotropic Glutamate- Receptors, Metabotropic Glutamate
- Glutamate Receptors, Metabotropic
- Receptors, Glutamate, Metabotropic
- Metabotropic Glutamate Receptor
- Glutamate Receptor, Metabotropic
- Receptor, Metabotropic Glutamate
- Metabotropic Glutamate Receptors
Below are MeSH descriptors whose meaning is more general than "Receptors, Metabotropic Glutamate".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Metabotropic Glutamate".
This graph shows the total number of publications written about "Receptors, Metabotropic Glutamate" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Metabotropic Glutamate" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 |
| 1993 | 1 | 0 | 1 |
| 1994 | 5 | 1 | 6 |
| 1995 | 4 | 4 | 8 |
| 1996 | 2 | 0 | 2 |
| 1997 | 5 | 0 | 5 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 4 | 4 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 4 | 4 | 8 |
| 2005 | 6 | 2 | 8 |
| 2006 | 2 | 5 | 7 |
| 2007 | 7 | 2 | 9 |
| 2008 | 2 | 2 | 4 |
| 2009 | 4 | 5 | 9 |
| 2010 | 4 | 2 | 6 |
| 2011 | 5 | 4 | 9 |
| 2012 | 5 | 2 | 7 |
| 2013 | 3 | 3 | 6 |
| 2014 | 2 | 0 | 2 |
| 2015 | 8 | 2 | 10 |
| 2016 | 2 | 2 | 4 |
| 2017 | 2 | 2 | 4 |
| 2018 | 3 | 0 | 3 |
| 2020 | 4 | 0 | 4 |
Below are the most recent publications written about "Receptors, Metabotropic Glutamate" by people in Profiles.
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Identification and Development of a New Positron Emission Tomography Ligand 4-(2-Fluoro-4-[11C]methoxyphenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu2). J Med Chem. 2020 10 22; 63(20):11469-11483.
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Clinical features, prognostic factors, and antibody effects in anti-mGluR1 encephalitis. Neurology. 2020 12 01; 95(22):e3012-e3025.
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Synthesis and Characterization of Fluorine-18-Labeled N-(4-Chloro-3-((fluoromethyl-d2)thio)phenyl)picolinamide for Imaging of mGluR4 in Brain. J Med Chem. 2020 03 26; 63(6):3381-3389.
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Synaptic organisation and behaviour-dependent activity of mGluR8a-innervated GABAergic trilaminar cells projecting from the hippocampus to the subiculum. Brain Struct Funct. 2020 Mar; 225(2):705-734.
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Deletion of the type 2 metabotropic glutamate receptor increases heroin abuse vulnerability in transgenic rats. Neuropsychopharmacology. 2018 12; 43(13):2615-2626.
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The activation of group II metabotropic glutamate receptors protects neonatal rat brains from oxidative stress injury after hypoxia-ischemia. PLoS One. 2018; 13(7):e0200933.
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A phase II trial of riluzole, an antagonist of metabotropic glutamate receptor 1 (GRM1) signaling, in patients with advanced melanoma. Pigment Cell Melanoma Res. 2018 07; 31(4):534-540.
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ER-mitochondria tethering by PDZD8 regulates Ca2+ dynamics in mammalian neurons. Science. 2017 11 03; 358(6363):623-630.
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Synthesis and Preliminary Studies of a Novel Negative Allosteric Modulator, 7-((2,5-Dioxopyrrolidin-1-yl)methyl)-4-(2-fluoro-4-[11C]methoxyphenyl) quinoline-2-carboxamide, for Imaging of Metabotropic Glutamate Receptor 2. ACS Chem Neurosci. 2017 09 20; 8(9):1937-1948.
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Group II metabotropic glutamate receptor interactions with NHERF scaffold proteins: Implications for receptor localization in brain. Neuroscience. 2017 06 14; 353:58-75.