Receptors, Metabotropic Glutamate
"Receptors, Metabotropic Glutamate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind glutamate and act through G-proteins to influence second messenger systems. Several types of metabotropic glutamate receptors have been cloned. They differ in pharmacology, distribution, and mechanisms of action.
MeSH Number(s)
D12.776.543.750.100.450
D12.776.543.750.720.200.450.500
Concept/Terms
Receptors, Metabotropic Glutamate- Receptors, Metabotropic Glutamate
- Glutamate Receptors, Metabotropic
- Receptors, Glutamate, Metabotropic
- Metabotropic Glutamate Receptor
- Glutamate Receptor, Metabotropic
- Receptor, Metabotropic Glutamate
- Metabotropic Glutamate Receptors
Below are MeSH descriptors whose meaning is more general than "Receptors, Metabotropic Glutamate".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Metabotropic Glutamate".
This graph shows the total number of publications written about "Receptors, Metabotropic Glutamate" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Metabotropic Glutamate" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 2 | 0 | 2 |
| 1994 | 5 | 2 | 7 |
| 1995 | 4 | 4 | 8 |
| 1996 | 3 | 0 | 3 |
| 1997 | 5 | 0 | 5 |
| 1998 | 0 | 2 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 4 | 4 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 4 | 4 | 8 |
| 2005 | 6 | 2 | 8 |
| 2006 | 2 | 5 | 7 |
| 2007 | 7 | 3 | 10 |
| 2008 | 1 | 2 | 3 |
| 2009 | 4 | 4 | 8 |
| 2010 | 5 | 2 | 7 |
| 2011 | 4 | 5 | 9 |
| 2012 | 4 | 2 | 6 |
| 2013 | 3 | 4 | 7 |
| 2014 | 2 | 0 | 2 |
| 2015 | 8 | 2 | 10 |
| 2016 | 2 | 3 | 5 |
| 2017 | 4 | 3 | 7 |
| 2018 | 2 | 0 | 2 |
| 2020 | 5 | 0 | 5 |
| 2021 | 4 | 3 | 7 |
| 2022 | 5 | 0 | 5 |
| 2023 | 1 | 0 | 1 |
Below are the most recent publications written about "Receptors, Metabotropic Glutamate" by people in Profiles.
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Detailed radiosynthesis of [18 F]mG4P027 as a positron emission tomography radiotracer for mGluR4. J Labelled Comp Radiopharm. 2023 02; 66(2):34-40.
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PET imaging studies to investigate functional expression of mGluR2 using [11C]mG2P001. J Cereb Blood Flow Metab. 2023 02; 43(2):296-308.
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Design, Synthesis, and Characterization of [18F]mG2P026 as a High-Contrast PET Imaging Ligand for Metabotropic Glutamate Receptor 2. J Med Chem. 2022 07 28; 65(14):9939-9954.
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Excess ribosomal protein production unbalances translation in a model of Fragile X Syndrome. Nat Commun. 2022 06 10; 13(1):3236.
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Exploration of group II metabotropic glutamate receptor modulation in mouse models of Rett syndrome and MECP2 Duplication syndrome. Neuropharmacology. 2022 05 15; 209:109022.
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Synthesis and Characterization of 5-(2-Fluoro-4-[11C]methoxyphenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine-7-carboxamide as a PET Imaging Ligand for Metabotropic Glutamate Receptor 2. J Med Chem. 2022 02 10; 65(3):2593-2609.
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mGlu1 potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits. Cell Rep. 2021 11 02; 37(5):109950.
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Graded heterogeneity of metabotropic signaling underlies a continuum of cell-intrinsic temporal responses in unipolar brush cells. Nat Commun. 2021 10 07; 12(1):5491.
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Purkinje cell outputs selectively inhibit a subset of unipolar brush cells in the input layer of the cerebellar cortex. Elife. 2021 08 09; 10.
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Frontal cortex genetic ablation of metabotropic glutamate receptor subtype 3 (mGlu3) impairs postsynaptic plasticity and modulates affective behaviors. Neuropsychopharmacology. 2021 11; 46(12):2148-2157.