Harvard Catalyst Profiles

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Receptors, KIR

"Receptors, KIR" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A family of receptors found on NK CELLS that have specificity for a variety of HLA ANTIGENS. KIR receptors contain up to three different extracellular immunoglobulin-like domains referred to as D0, D1, and D2 and play an important role in blocking NK cell activation against cells expressing the appropriate HLA antigens thus preventing cell lysis. Although they are often referred to as being inhibitory receptors, a subset of KIR receptors may also play an activating role in NK cells.


This graph shows the total number of publications written about "Receptors, KIR" by people in Harvard Catalyst Profiles by year, and whether "Receptors, KIR" was a major or minor topic of these publication.
Bar chart showing 76 publications over 24 distinct years, with a maximum of 9 publications in 2011
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.