Receptors, Interleukin-21
"Receptors, Interleukin-21" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors for interleukin 21. They are heterodimeric proteins found on DENDRITIC CELLS and LYMPHOCYTES that consist of the INTERLEUKIN-21 RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR COMMON BETA SUBUNIT.
MeSH Number(s)
D12.776.543.750.705.852.420.900
Concept/Terms
Receptors, Interleukin-21- Receptors, Interleukin-21
- Receptors, Interleukin 21
- IL-21 Receptors
- IL 21 Receptors
- Receptors, IL-21
- IL21R
- Interleukin-21 Receptors
- Interleukin 21 Receptors
- Receptor, Interleukin-21
- Receptor, Interleukin 21
- IL-21 Receptor
- IL 21 Receptor
- Receptor, IL-21
- Interleukin-21 Receptor
- Interleukin 21 Receptor
Below are MeSH descriptors whose meaning is more general than "Receptors, Interleukin-21".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Interleukin-21".
This graph shows the total number of publications written about "Receptors, Interleukin-21" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Interleukin-21" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, Interleukin-21" by people in Profiles.
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Phenotypic signatures of immune selection in HIV-1 reservoir cells. Nature. 2023 Feb; 614(7947):309-317.
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Anti-CD20-interleukin-21 fusokine targets malignant B cells via direct apoptosis and NK-cell-dependent cytotoxicity. Blood. 2017 04 20; 129(16):2246-2256.
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Interleukin 21 - its potential role in the therapy of B-cell lymphomas. Leuk Lymphoma. 2017 01; 58(1):17-29.
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Direct and immune-mediated cytotoxicity of interleukin-21 contributes to antitumor effects in mantle cell lymphoma. Blood. 2015 Sep 24; 126(13):1555-64.
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Human IL-21 and IL-21R deficiencies: two novel entities of primary immunodeficiency. Curr Opin Pediatr. 2014 Dec; 26(6):704-12.
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IL-21 receptor signalling partially mediates Th2-mediated allergic airway responses. Clin Exp Allergy. 2014 Jul; 44(7):976-85.
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Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans. Blood. 2014 Jun 19; 123(25):3988-98.
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IL-21 is a major negative regulator of IRF4-dependent lipolysis affecting Tregs in adipose tissue and systemic insulin sensitivity. Diabetes. 2014 Jun; 63(6):2086-96.
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The cytokines IL-21 and GM-CSF have opposing regulatory roles in the apoptosis of conventional dendritic cells. Immunity. 2013 Mar 21; 38(3):514-27.
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Ex vivo expansion of human CD8+ T cells using autologous CD4+ T cell help. PLoS One. 2012; 7(1):e30229.