Receptors, Guanylate Cyclase-Coupled
"Receptors, Guanylate Cyclase-Coupled" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of cellular membrane receptors that either have an intrinsic guanylate cyclase activity or are closely coupled to specific guanylate cyclases within the cell.
MeSH Number(s)
D08.811.520.650.600.500
D12.776.543.750.120
Concept/Terms
Receptors, Guanylate Cyclase-Coupled- Receptors, Guanylate Cyclase-Coupled
- Cyclase-Coupled Receptors, Guanylate
- Receptors, Guanylate Cyclase Coupled
- Guanylyl Cyclase Receptors
- Cyclase Receptors, Guanylyl
- Receptors, Guanylyl Cyclase
- Guanylyl Cyclase-Linked Receptors
- Cyclase-Linked Receptors, Guanylyl
- Guanylyl Cyclase Linked Receptors
- Receptors, Guanylyl Cyclase-Linked
- Guanylate Cyclase-Coupled Receptors
- Guanylate Cyclase Coupled Receptors
Below are MeSH descriptors whose meaning is more general than "Receptors, Guanylate Cyclase-Coupled".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Guanylate Cyclase-Coupled".
This graph shows the total number of publications written about "Receptors, Guanylate Cyclase-Coupled" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Guanylate Cyclase-Coupled" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
Below are the most recent publications written about "Receptors, Guanylate Cyclase-Coupled" by people in Profiles.
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Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis. Cancer Res. 2016 Jan 15; 76(2):339-46.
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Molecular testing for lymph node metastases as a determinant of colon cancer recurrence: results from a retrospective multicenter study. Clin Cancer Res. 2014 Aug 15; 20(16):4361-9.
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Effect of guanylate cyclase-C activity on energy and glucose homeostasis. Diabetes. 2014 Nov; 63(11):3798-804.
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A chemoreceptor that detects molecular carbon dioxide. J Biol Chem. 2013 Dec 27; 288(52):37071-81.
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Meconium ileus caused by mutations in GUCY2C, encoding the CFTR-activating guanylate cyclase 2C. Am J Hum Genet. 2012 May 04; 90(5):893-9.
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A single gene target of an ETS-family transcription factor determines neuronal CO2-chemosensitivity. PLoS One. 2012; 7(3):e34014.
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Two randomized trials of linaclotide for chronic constipation. N Engl J Med. 2011 Aug 11; 365(6):527-36.
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Evaluation of guanylyl cyclase C lymph node status for colon cancer staging and prognosis. Ann Surg Oncol. 2011 Nov; 18(12):3261-70.
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Investigational agents for the irritable bowel syndrome. Expert Opin Investig Drugs. 2010 Oct; 19(10):1161-78.
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Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit. Eur J Pharmacol. 2010 Dec 15; 649(1-3):328-35.