Receptors, Glucocorticoid
"Receptors, Glucocorticoid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.
MeSH Number(s)
D12.776.260.698.750.430
D12.776.826.750.430
D12.776.930.669.750.430
Concept/Terms
Receptors, Glucocorticoid- Receptors, Glucocorticoid
- Glucocorticoid Receptors
- Glucocorticoid Receptor
- Receptor, Glucocorticoid
- Receptors, Glucocorticoids
- Glucocorticoids Receptors
Receptors, Corticoid Type II- Receptors, Corticoid Type II
- Corticoid Type II Receptors
- Corticoid II Receptor
- Receptor, Corticoid II
- Receptors, Corticoid II
- Corticoid II Receptors
Below are MeSH descriptors whose meaning is more general than "Receptors, Glucocorticoid".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- DNA-Binding Proteins [D12.776.260]
- Receptors, Cytoplasmic and Nuclear [D12.776.260.698]
- Receptors, Steroid [D12.776.260.698.750]
- Receptors, Glucocorticoid [D12.776.260.698.750.430]
- Receptors, Cytoplasmic and Nuclear [D12.776.826]
- Receptors, Steroid [D12.776.826.750]
- Receptors, Glucocorticoid [D12.776.826.750.430]
- Transcription Factors [D12.776.930]
- Receptors, Cytoplasmic and Nuclear [D12.776.930.669]
- Receptors, Steroid [D12.776.930.669.750]
- Receptors, Glucocorticoid [D12.776.930.669.750.430]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Glucocorticoid".
This graph shows the total number of publications written about "Receptors, Glucocorticoid" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Glucocorticoid" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 3 | 4 |
| 1994 | 0 | 1 | 1 |
| 1995 | 6 | 2 | 8 |
| 1996 | 2 | 4 | 6 |
| 1997 | 2 | 2 | 4 |
| 1999 | 1 | 1 | 2 |
| 2000 | 0 | 4 | 4 |
| 2001 | 0 | 4 | 4 |
| 2002 | 2 | 6 | 8 |
| 2003 | 0 | 4 | 4 |
| 2004 | 3 | 3 | 6 |
| 2005 | 8 | 1 | 9 |
| 2006 | 2 | 3 | 5 |
| 2007 | 2 | 1 | 3 |
| 2008 | 1 | 6 | 7 |
| 2009 | 1 | 2 | 3 |
| 2010 | 5 | 5 | 10 |
| 2011 | 4 | 1 | 5 |
| 2012 | 5 | 7 | 12 |
| 2013 | 4 | 3 | 7 |
| 2014 | 7 | 3 | 10 |
| 2015 | 6 | 9 | 15 |
| 2016 | 7 | 7 | 14 |
| 2017 | 8 | 5 | 13 |
| 2018 | 4 | 3 | 7 |
| 2019 | 5 | 5 | 10 |
| 2020 | 6 | 5 | 11 |
| 2021 | 3 | 2 | 5 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, Glucocorticoid" by people in Profiles.
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The role of the glucocorticoid receptor and its impact on steroid response in moderate-severe COVID-19 patients. Eur J Pharmacol. 2023 Mar 15; 943:175555.
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Multimodal single cell sequencing implicates chromatin accessibility and genetic background in diabetic kidney disease progression. Nat Commun. 2022 09 06; 13(1):5253.
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Interplay between nuclear factor-?B, p38 MAPK, and glucocorticoid receptor signaling synergistically induces functional TLR2 in lung epithelial cells. J Biol Chem. 2022 04; 298(4):101747.
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Multiomics analysis identifies BIRC3 as a novel glucocorticoid response-associated gene. J Allergy Clin Immunol. 2022 06; 149(6):1981-1991.
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A new p65 isoform that bind the glucocorticoid hormone and is expressed in inflammation liver diseases and COVID-19. Sci Rep. 2021 11 25; 11(1):22913.
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TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states. Elife. 2021 10 08; 10.
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Role of hypothalamic-pituitary adrenal-axis, toll-like receptors, and macrophage polarization in pre-atherosclerotic changes induced by social isolation stress in mice. Sci Rep. 2021 09 27; 11(1):19091.
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Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5. Cell Rep. 2021 06 01; 35(9):109185.
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Genomic determinants implicated in the glucocorticoid-mediated induction of KLF9 in pulmonary epithelial cells. J Biol Chem. 2021 Jan-Jun; 296:100065.
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The Arg/N-degron pathway targets transcription factors and regulates specific genes. Proc Natl Acad Sci U S A. 2020 12 08; 117(49):31094-31104.