Receptors, Formyl Peptide
"Receptors, Formyl Peptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE. Since N-formyl peptides are found in MITOCHONDRIA and BACTERIA, this class of receptors is believed to play a role in mediating cellular responses to cellular damage and bacterial invasion. However, non-formylated peptide ligands have also been found for this receptor class.
MeSH Number(s)
D12.776.543.750.100.235
D12.776.543.750.705.873
D12.776.543.750.750.340
Concept/Terms
Receptors, Formyl Peptide- Receptors, Formyl Peptide
- Formyl Peptide Receptors
- Peptide Receptors, Formyl
- Chemotactic Peptide Receptor
- Peptide Receptor, Chemotactic
- F-Chemotactic Peptide Receptor
- F Chemotactic Peptide Receptor
- Receptor, F-Chemotactic Peptide
- Receptor, Chemotactic Peptide
- FMLP Receptor
- Receptor, FMLP
- Formyl Peptide Receptor
- Receptor, Formyl Peptide
- N-formyl Hexapeptide Receptor
- Hexapeptide Receptor, N-formyl
- N formyl Hexapeptide Receptor
- Receptor, N-formyl Hexapeptide
- N-Formylmethionyl Peptide Receptor
- N Formylmethionyl Peptide Receptor
- Peptide Receptor, N-Formylmethionyl
- Receptor, N-Formylmethionyl Peptide
- Chemoattractant Receptor
- Receptor, Chemoattractant
- fMet-Leu-Phe Receptor
- Receptor, fMet-Leu-Phe
- fMet Leu Phe Receptor
Below are MeSH descriptors whose meaning is more general than "Receptors, Formyl Peptide".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Formyl Peptide".
This graph shows the total number of publications written about "Receptors, Formyl Peptide" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Formyl Peptide" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 2 | 2 |
| 1994 | 0 | 1 | 1 |
| 1997 | 3 | 0 | 3 |
| 1998 | 2 | 0 | 2 |
| 1999 | 4 | 1 | 5 |
| 2000 | 3 | 1 | 4 |
| 2001 | 1 | 0 | 1 |
| 2002 | 3 | 1 | 4 |
| 2003 | 5 | 0 | 5 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 2 | 4 |
| 2010 | 2 | 2 | 4 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 4 | 5 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 2 | 4 |
| 2015 | 3 | 3 | 6 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 2 | 2 |
| 2018 | 1 | 3 | 4 |
| 2019 | 2 | 1 | 3 |
| 2020 | 2 | 3 | 5 |
| 2021 | 0 | 4 | 4 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 2 | 3 |
Below are the most recent publications written about "Receptors, Formyl Peptide" by people in Profiles.
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ALX/FPR2 Activation by Stereoisomers of D1 Resolvins Elucidating with Molecular Dynamics Simulation. J Phys Chem B. 2023 07 27; 127(29):6479-6486.
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Anti-Inflammatory and Pro-Resolving Actions of the N-Terminal Peptides Ac2-26, Ac2-12, and Ac9-25 of Annexin A1 on Conjunctival Goblet Cell Function. Am J Pathol. 2023 Nov; 193(11):1817-1832.
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Can Neutrophils Prevent Nosocomial Pneumonia after Serious Injury? Int J Mol Sci. 2023 Apr 21; 24(8).
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Optimized flow cytometry assays to monitor neutrophil activation in human and mouse whole blood samples. J Immunol Methods. 2023 01; 512:113403.
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Antibiotic-chemoattractants enhance neutrophil clearance of Staphylococcus aureus. Nat Commun. 2021 10 25; 12(1):6157.
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Discovery of potential imaging and therapeutic targets for severe inflammation in COVID-19 patients. Sci Rep. 2021 07 08; 11(1):14151.
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Circulating mitochondrial N-formyl peptides contribute to secondary nosocomial infection in patients with septic shock. Proc Natl Acad Sci U S A. 2021 04 27; 118(17).
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VIP modulates human macrophages phenotype via FPRL1 via activation of RhoA-GTPase and PLC pathways. Inflamm Res. 2021 Mar; 70(3):309-321.
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A major genetic accelerator of cancer diagnosis: rs867228 in FPR1. Oncoimmunology. 2021 01 06; 10(1):1859064.
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A TLR3 Ligand Reestablishes Chemotherapeutic Responses in the Context of FPR1 Deficiency. Cancer Discov. 2021 02; 11(2):408-423.