Harvard Catalyst Profiles

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Receptors, Death Domain

"Receptors, Death Domain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a death domain due to the fact that many of these receptors are involved in signaling APOPTOSIS. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES.


This graph shows the total number of publications written about "Receptors, Death Domain" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Death Domain" was a major or minor topic of these publication.
Bar chart showing 17 publications over 10 distinct years, with a maximum of 4 publications in 2010
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.