Receptors, Cytoplasmic and Nuclear
"Receptors, Cytoplasmic and Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.
MeSH Number(s)
D12.776.260.698
D12.776.826
D12.776.930.669
Concept/Terms
Receptors, Cytoplasmic and Nuclear- Receptors, Cytoplasmic and Nuclear
- Cytosol and Nuclear Receptors
- Receptors, Nuclear and Cytoplasmic
- Nuclear and Cytoplasmic Receptors
- Receptors, Cytosol and Nuclear
- Receptors, Cytosolic and Nuclear
- Cytoplasmic and Nuclear Receptors
- Cytosolic and Nuclear Receptors
Below are MeSH descriptors whose meaning is more general than "Receptors, Cytoplasmic and Nuclear".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Cytoplasmic and Nuclear".
This graph shows the total number of publications written about "Receptors, Cytoplasmic and Nuclear" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Cytoplasmic and Nuclear" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 3 | 3 | 6 |
| 1994 | 9 | 2 | 11 |
| 1995 | 8 | 5 | 13 |
| 1996 | 9 | 5 | 14 |
| 1997 | 17 | 4 | 21 |
| 1998 | 17 | 12 | 29 |
| 1999 | 19 | 12 | 31 |
| 2000 | 27 | 10 | 37 |
| 2001 | 26 | 13 | 39 |
| 2002 | 38 | 15 | 53 |
| 2003 | 36 | 17 | 53 |
| 2004 | 27 | 8 | 35 |
| 2005 | 11 | 17 | 28 |
| 2006 | 14 | 10 | 24 |
| 2007 | 6 | 6 | 12 |
| 2008 | 9 | 3 | 12 |
| 2009 | 9 | 5 | 14 |
| 2010 | 9 | 5 | 14 |
| 2011 | 8 | 3 | 11 |
| 2012 | 8 | 8 | 16 |
| 2013 | 13 | 6 | 19 |
| 2014 | 11 | 2 | 13 |
| 2015 | 3 | 5 | 8 |
| 2016 | 11 | 3 | 14 |
| 2017 | 4 | 1 | 5 |
| 2018 | 5 | 6 | 11 |
| 2019 | 10 | 6 | 16 |
| 2020 | 4 | 3 | 7 |
| 2021 | 4 | 6 | 10 |
| 2022 | 3 | 5 | 8 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, Cytoplasmic and Nuclear" by people in Profiles.
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Management of Primary Biliary Cholangitis: Current Treatment and Future Perspectives. Turk J Gastroenterol. 2023 Feb; 34(2):89-100.
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Structure and function of the peroxisomal ubiquitin ligase complex. Biochem Soc Trans. 2022 12 16; 50(6):1921-1930.
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PEX5 translocation into and out of peroxisomes drives matrix protein import. Mol Cell. 2022 09 01; 82(17):3209-3225.e7.
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A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel. Nature. 2022 07; 607(7918):374-380.
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Skin Aging in Long-Lived Naked Mole-Rats Is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes. J Invest Dermatol. 2022 11; 142(11):2853-2863.e4.
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P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia. Nat Cancer. 2022 07; 3(7):837-851.
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Disruption of Circadian Rhythms by Shift Work Exacerbates Reperfusion Injury in Myocardial Infarction. J Am Coll Cardiol. 2022 05 31; 79(21):2097-2115.
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The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes. Cell Stem Cell. 2022 05 05; 29(5):795-809.e11.
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Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis. Proc Natl Acad Sci U S A. 2022 03 29; 119(13):e2023784119.
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Chemical synthesis, biological activities and action on nuclear receptors of 20S(OH)D3, 20S,25(OH)2D3, 20S,23S(OH)2D3 and 20S,23R(OH)2D3. Bioorg Chem. 2022 04; 121:105660.