Receptors, Antigen, T-Cell, alpha-beta
"Receptors, Antigen, T-Cell, alpha-beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primarily in CD4+ or CD8+ T-cells. Unlike immunoglobulins, the alpha-beta T-cell receptors recognize antigens only when presented in association with major histocompatibility (MHC) molecules.
MeSH Number(s)
D12.776.543.750.705.816.824.825
Concept/Terms
Receptors, Antigen, T-Cell, alpha-beta- Receptors, Antigen, T-Cell, alpha-beta
- Antigen Receptors, T-Cell, alpha-beta
- TcR alpha-beta
- TcR alpha beta
- alpha-beta, TcR
- T-Cell Receptor, alpha-beta
- T Cell Receptor, alpha beta
- alpha-beta T-Cell Receptor
- T-Cell Receptors, alpha-beta
- alpha-beta T-Cell Receptors
- Receptors, Antigen, T Cell, alpha beta
- T Cell Receptors, alpha beta
Antigen T Cell Receptor, beta Chain- Antigen T Cell Receptor, beta Chain
- T-Cell Receptors beta-Chain
- T Cell Receptors beta Chain
- beta-Chain, T-Cell Receptors
- T-Cell Receptor beta-Chain
- T Cell Receptor beta Chain
- beta-Chain, T-Cell Receptor
T-Cell Receptors alpha-Chain- T-Cell Receptors alpha-Chain
- T Cell Receptors alpha Chain
- alpha-Chain, T-Cell Receptors
- Antigen T Cell Receptor, alpha Chain
- T-Cell Receptor alpha-Chain
- T Cell Receptor alpha Chain
- alpha-Chain, T-Cell Receptor
Below are MeSH descriptors whose meaning is more general than "Receptors, Antigen, T-Cell, alpha-beta".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Antigen [D12.776.543.750.705.816]
- Receptors, Antigen, T-Cell [D12.776.543.750.705.816.824]
- Receptors, Antigen, T-Cell, alpha-beta [D12.776.543.750.705.816.824.825]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Antigen, T-Cell, alpha-beta".
This graph shows the total number of publications written about "Receptors, Antigen, T-Cell, alpha-beta" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Antigen, T-Cell, alpha-beta" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 3 | 12 | 15 |
| 1992 | 11 | 6 | 17 |
| 1993 | 21 | 7 | 28 |
| 1994 | 16 | 11 | 27 |
| 1995 | 12 | 13 | 25 |
| 1996 | 21 | 12 | 33 |
| 1997 | 17 | 13 | 30 |
| 1998 | 14 | 9 | 23 |
| 1999 | 12 | 13 | 25 |
| 2000 | 10 | 13 | 23 |
| 2001 | 9 | 12 | 21 |
| 2002 | 7 | 8 | 15 |
| 2003 | 1 | 9 | 10 |
| 2004 | 3 | 12 | 15 |
| 2005 | 4 | 9 | 13 |
| 2006 | 5 | 2 | 7 |
| 2007 | 12 | 6 | 18 |
| 2008 | 6 | 2 | 8 |
| 2009 | 7 | 6 | 13 |
| 2010 | 8 | 4 | 12 |
| 2011 | 4 | 6 | 10 |
| 2012 | 7 | 2 | 9 |
| 2013 | 7 | 4 | 11 |
| 2014 | 3 | 5 | 8 |
| 2015 | 8 | 5 | 13 |
| 2016 | 6 | 6 | 12 |
| 2017 | 6 | 4 | 10 |
| 2018 | 2 | 3 | 5 |
| 2019 | 8 | 1 | 9 |
| 2020 | 4 | 5 | 9 |
| 2021 | 2 | 4 | 6 |
Below are the most recent publications written about "Receptors, Antigen, T-Cell, alpha-beta" by people in Profiles.
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High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency. J Exp Med. 2021 08 02; 218(8).
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HLA class I-associated expansion of TRBV11-2 T cells in multisystem inflammatory syndrome in children. J Clin Invest. 2021 05 17; 131(10).
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T cell reactivity to regulatory factor X4 in type 1 narcolepsy. Sci Rep. 2021 04 09; 11(1):7841.
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Circulating clonally expanded T cells reflect functions of tumor-infiltrating T cells. J Exp Med. 2021 04 05; 218(4).
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Regulation of EAE by spontaneously generated IL-10-secreting regulatory T cells in HLA-DR15/TCR.Ob1A12 double transgenic mice. Immunology. 2021 07; 163(3):338-343.
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Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner. Proc Natl Acad Sci U S A. 2021 01 26; 118(4).
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A general chemical crosslinking strategy for structural analyses of weakly interacting proteins applied to preTCR-pMHC complexes. J Biol Chem. 2021 Jan-Jun; 296:100255.
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Pre-T cell receptors topologically sample self-ligands during thymocyte ß-selection. Science. 2021 01 08; 371(6525):181-185.
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Somatic mutations and T-cell clonality in patients with immunodeficiency. Haematologica. 2020 12 01; 105(12):2757-2768.
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The aßTCR mechanosensor exploits dynamic ectodomain allostery to optimize its ligand recognition site. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21336-21345.