Receptor-Interacting Protein Serine-Threonine Kinases
"Receptor-Interacting Protein Serine-Threonine Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.
MeSH Number(s)
D08.811.913.696.620.682.700.801
D12.644.360.024.296.400
D12.644.360.024.500.186
D12.644.360.075.421.400
D12.776.157.057.024.400
D12.776.157.057.500.186
D12.776.476.024.375.662
D12.776.476.024.500.186
D12.776.476.075.421.400
Concept/Terms
Receptor-Interacting Protein Serine-Threonine Kinases- Receptor-Interacting Protein Serine-Threonine Kinases
- Receptor Interacting Protein Serine Threonine Kinases
- RIP Serine-Threonine Kinases
- Kinases, RIP Serine-Threonine
- RIP Serine Threonine Kinases
- Serine-Threonine Kinases, RIP
Receptor-Interacting Protein Serine-Threonine Kinase 1- Receptor-Interacting Protein Serine-Threonine Kinase 1
- Receptor Interacting Protein Serine Threonine Kinase 1
- RIP (Receptor Interacting Protein)
- RIP Serine-Threonine Kinase
- Kinase, RIP Serine-Threonine
- RIP Serine Threonine Kinase
- Serine-Threonine Kinase, RIP
- Receptor Interacting Protein RIP
Below are MeSH descriptors whose meaning is more general than "Receptor-Interacting Protein Serine-Threonine Kinases".
Below are MeSH descriptors whose meaning is more specific than "Receptor-Interacting Protein Serine-Threonine Kinases".
This graph shows the total number of publications written about "Receptor-Interacting Protein Serine-Threonine Kinases" by people in Harvard Catalyst Profiles by year, and whether "Receptor-Interacting Protein Serine-Threonine Kinases" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 1 | 3 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 2 | 3 |
| 2015 | 2 | 0 | 2 |
| 2016 | 3 | 0 | 3 |
| 2017 | 6 | 1 | 7 |
| 2018 | 8 | 2 | 10 |
| 2019 | 5 | 5 | 10 |
| 2020 | 3 | 3 | 6 |
| 2021 | 7 | 1 | 8 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptor-Interacting Protein Serine-Threonine Kinases" by people in Profiles.
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RIPK necrotic cell death pathway in both donor photoreceptor and host immune cells synergize to affect photoreceptor graft survival. FASEB J. 2023 04; 37(4):e22847.
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RIPK1 mutations causing infantile-onset IBD with inflammatory and fistulizing features. Front Immunol. 2022; 13:1041315.
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Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL. J Extracell Vesicles. 2022 09; 11(9):e12261.
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Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death. Redox Biol. 2022 04; 50:102232.
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Genetic inhibition of RIPK3 ameliorates functional outcome in controlled cortical impact independent of necroptosis. Cell Death Dis. 2021 11 09; 12(11):1064.
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Visualization of Receptor-Interacting Protein Kinase 1 (RIPK1) by Brain Imaging with Positron Emission Tomography. J Med Chem. 2021 10 28; 64(20):15420-15428.
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MLKL and CaMKII Are Involved in RIPK3-Mediated Smooth Muscle Cell Necroptosis. Cells. 2021 09 12; 10(9).
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The Lysosomal Rag-Ragulator Complex Licenses RIPK1 and Caspase-8-mediated Pyroptosis by Yersinia. Science. 2021 06 25; 372(6549).
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A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A. 2021 03 30; 118(13).
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Differential role of MLKL in alcohol-associated and non-alcohol-associated fatty liver diseases in mice and humans. JCI Insight. 2021 02 22; 6(4).