Receptor, Serotonin, 5-HT1B
"Receptor, Serotonin, 5-HT1B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine effect.
MeSH Number(s)
D12.776.543.750.070.800.100.150
D12.776.543.750.100.800.100.150
D12.776.543.750.720.300.800.100.150
D12.776.543.750.720.670.100.500
Concept/Terms
Receptor, Serotonin, 5-HT1B- Receptor, Serotonin, 5-HT1B
- 5-HT(1Dbeta) Receptor
- 5-HT1B Receptor
- 5 HT1B Receptor
- Receptor, 5-HT1B
- 5-HT1Dbeta Receptor
- 5 HT1Dbeta Receptor
- Receptor, 5-HT1Dbeta
- 5-Hydroxytryptamine 1B Receptor
- 1B Receptor, 5-Hydroxytryptamine
- 5 Hydroxytryptamine 1B Receptor
- Serotonin 1Dbeta Receptors
- 1Dbeta Receptors, Serotonin
- Receptors, Serotonin 1Dbeta
- Receptor, 5-Hydroxytryptamine 1B
- Receptor, 5 Hydroxytryptamine 1B
- Receptor, Serotonin Type 1Dbeta
- Serotonin 1B Receptor
- 1B Receptor, Serotonin
- Receptor, Serotonin 1B
- Serotonin 1D Beta Receptor
- Serotonin 1Dbeta Receptor
- 1Dbeta Receptor, Serotonin
- Receptor, Serotonin 1Dbeta
- 5-HT(1B) Receptor
- 5-Hydroxytryptamine 1B Receptors
- 1B Receptors, 5-Hydroxytryptamine
- 5 Hydroxytryptamine 1B Receptors
- Receptors, 5-Hydroxytryptamine 1B
Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT1B".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.070]
- Receptors, Serotonin [D12.776.543.750.070.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.070.800.100]
- Receptor, Serotonin, 5-HT1B [D12.776.543.750.070.800.100.150]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Serotonin [D12.776.543.750.100.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.100.800.100]
- Receptor, Serotonin, 5-HT1B [D12.776.543.750.100.800.100.150]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Biogenic Amine [D12.776.543.750.720.300]
- Receptors, Serotonin [D12.776.543.750.720.300.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.720.300.800.100]
- Receptor, Serotonin, 5-HT1B [D12.776.543.750.720.300.800.100.150]
- Receptors, Presynaptic [D12.776.543.750.720.670]
- Autoreceptors [D12.776.543.750.720.670.100]
- Receptor, Serotonin, 5-HT1B [D12.776.543.750.720.670.100.500]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT1B".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT1B" by people in Harvard Catalyst Profiles by year, and whether "Receptor, Serotonin, 5-HT1B" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 2 | 2 | 4 |
| 2006 | 2 | 0 | 2 |
| 2007 | 2 | 2 | 4 |
| 2009 | 1 | 1 | 2 |
| 2017 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
Below are the most recent publications written about "Receptor, Serotonin, 5-HT1B" by people in Profiles.
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Brainstem serotonin neurons selectively gate retinal information flow to thalamus. Neuron. 2023 03 01; 111(5):711-726.e11.
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Parkinson patients have a presynaptic serotonergic deficit: A dynamic deep brain stimulation PET study. J Cereb Blood Flow Metab. 2021 08; 41(8):1954-1963.
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Visual stimuli induce serotonin release in occipital cortex: A simultaneous positron emission tomography/magnetic resonance imaging study. Hum Brain Mapp. 2020 11; 41(16):4753-4763.
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Protective effects of sumatriptan on ischaemia/reperfusion injury following torsion/detorsion in ipsilateral and contralateral testes of rat. Andrologia. 2019 Oct; 51(9):e13358.
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Sumatriptan Increases Skin Flap Survival through Activation of 5-Hydroxytryptamine 1b/1d Receptors in Rats: The Mediating Role of the Nitric Oxide Pathway. Plast Reconstr Surg. 2019 07; 144(1):70e-77e.
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Association Between Sumatriptan Treatment During a Migraine Attack and Central 5-HT1B Receptor Binding. JAMA Neurol. 2019 07 01; 76(7):834-840.
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Functional Characterization of 5-HT1B Receptor Drugs in Nonhuman Primates Using Simultaneous PET-MR. J Neurosci. 2017 11 01; 37(44):10671-10678.
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Pharmacological evidence of involvement of nitric oxide pathway in anti-pruritic effects of sumatriptan in chloroquine-induced scratching in mice. Fundam Clin Pharmacol. 2018 Feb; 32(1):69-76.
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Low 5-HT1B receptor binding in the migraine brain: A PET study. Cephalalgia. 2018 03; 38(3):519-527.
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Hypothalamus proteomics from mouse models with obesity and anorexia reveals therapeutic targets of appetite regulation. Nutr Diabetes. 2016 Apr 25; 6:e204.