"Receptor, Notch2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A notch receptor that plays an important role in CELL DIFFERENTIATION in a variety of cell types. It is the preferentially expressed notch receptor in mature B-LYMPHOCYTES.
MeSH Number(s)
D12.776.543.750.725.750
D12.776.930.670.750
Below are MeSH descriptors whose meaning is more general than "Receptor, Notch2".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Notch2".
This graph shows the total number of publications written about "Receptor, Notch2" by people in Harvard Catalyst Profiles by year, and whether "Receptor, Notch2" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 5 | 0 | 5 |
| 2008 | 0 | 2 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 0 | 2 | 2 |
| 2011 | 2 | 1 | 3 |
| 2012 | 2 | 1 | 3 |
| 2013 | 5 | 0 | 5 |
| 2014 | 3 | 1 | 4 |
| 2015 | 1 | 4 | 5 |
| 2017 | 2 | 2 | 4 |
| 2018 | 2 | 2 | 4 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
Below are the most recent publications written about "Receptor, Notch2" by people in Profiles.
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Therapeutic Targeting Notch2 Protects Bone Micro-Vasculatures from Methotrexate Chemotherapy-Induced Adverse Effects in Rats. Cells. 2022 08 02; 11(15).
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Notch2 Blockade Mitigates Methotrexate Chemotherapy-Induced Bone Loss and Marrow Adiposity. Cells. 2022 05 02; 11(9).
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Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer. Cancer Res. 2022 01 15; 82(2):248-263.
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Notch-Hes1 signaling activation in Caroli disease and polycystic liver disease. Pathol Int. 2021 Aug; 71(8):521-529.
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TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells. Proc Natl Acad Sci U S A. 2020 12 08; 117(49):31331-31342.
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Pathological Conversion of Mouse Perivascular Adipose Tissue by Notch Activation. Arterioscler Thromb Vasc Biol. 2020 09; 40(9):2227-2243.
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A randomized phase II trial of nab-paclitaxel and gemcitabine with tarextumab or placebo in patients with untreated metastatic pancreatic cancer. Cancer Med. 2019 09; 8(11):5148-5157.
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Protease-Activated Receptor 1 Deletion Causes Enhanced Osteoclastogenesis in Response to Inflammatory Signals through a Notch2-Dependent Mechanism. J Immunol. 2019 07 01; 203(1):105-116.
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Notch Signaling Pathway in Apical Periodontitis: Correlation with Bone Resorption Regulators and Proinflammatory Cytokines. J Endod. 2019 Feb; 45(2):123-128.
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The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro. Elife. 2018 10 05; 7.