"Receptor, Notch1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A notch receptor that interacts with a variety of ligands and regulates SIGNAL TRANSDUCTION PATHWAYS for multiple cellular processes. It is widely expressed during EMBRYOGENESIS and is essential for EMBRYONIC DEVELOPMENT.
MeSH Number(s)
D12.776.543.750.725.500
D12.776.930.670.500
Below are MeSH descriptors whose meaning is more general than "Receptor, Notch1".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Notch1".
This graph shows the total number of publications written about "Receptor, Notch1" by people in Harvard Catalyst Profiles by year, and whether "Receptor, Notch1" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 3 | 3 |
| 1997 | 0 | 3 | 3 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 9 | 9 |
| 2000 | 0 | 8 | 8 |
| 2001 | 0 | 8 | 8 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 6 | 6 |
| 2004 | 0 | 7 | 7 |
| 2005 | 3 | 8 | 11 |
| 2006 | 16 | 4 | 20 |
| 2007 | 7 | 7 | 14 |
| 2008 | 10 | 1 | 11 |
| 2009 | 9 | 3 | 12 |
| 2010 | 8 | 6 | 14 |
| 2011 | 13 | 7 | 20 |
| 2012 | 9 | 3 | 12 |
| 2013 | 15 | 0 | 15 |
| 2014 | 17 | 6 | 23 |
| 2015 | 9 | 6 | 15 |
| 2016 | 8 | 3 | 11 |
| 2017 | 11 | 1 | 12 |
| 2018 | 7 | 1 | 8 |
| 2019 | 6 | 3 | 9 |
| 2020 | 3 | 4 | 7 |
| 2021 | 5 | 1 | 6 |
| 2022 | 0 | 4 | 4 |
| 2023 | 0 | 3 | 3 |
Below are the most recent publications written about "Receptor, Notch1" by people in Profiles.
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A spatiotemporal Notch interaction map from plasma membrane to nucleus. Sci Signal. 2023 08; 16(796):eadg6474.
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Type I Interferon Signature in NOTCH1-Related Leukoencephalopathy. Ann Neurol. 2023 05; 93(5):1041-1043.
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The Notch1/CD22 signaling axis disrupts Treg function in SARS-CoV-2-associated multisystem inflammatory syndrome in children. J Clin Invest. 2023 01 03; 133(1).
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A double-negative thymocyte-specific enhancer augments Notch1 signaling to direct early T cell progenitor expansion, lineage restriction and ß-selection. Nat Immunol. 2022 11; 23(11):1628-1643.
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Gamma Secretase Inhibition for a Child With Metastatic Glomus Tumor and Activated NOTCH1. JCO Precis Oncol. 2022 06; 6:e2200099.
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Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL. Blood. 2022 04 21; 139(16):2483-2498.
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NOTCH1 PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model. Oncotarget. 2022; 13:373-386.
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Notch1 and Notch3 coordinate for pericyte-induced stabilization of vasculature. Am J Physiol Cell Physiol. 2022 02 01; 322(2):C185-C196.
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Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer. Cancer Res. 2022 01 15; 82(2):248-263.
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Notch signaling promotes disease initiation and progression in murine chronic lymphocytic leukemia. Blood. 2021 06 03; 137(22):3079-3092.