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Receptor, IGF Type 1

"Receptor, IGF Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The beta subunit contains an intrinsic tyrosine kinase domain.


This graph shows the total number of publications written about "Receptor, IGF Type 1" by people in Harvard Catalyst Profiles by year, and whether "Receptor, IGF Type 1" was a major or minor topic of these publication.
Bar chart showing 226 publications over 27 distinct years, with a maximum of 26 publications in 2013
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.