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profileRNA Interference

"RNA Interference" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.


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This graph shows the total number of publications written about "RNA Interference" by people in Harvard Catalyst Profiles by year, and whether "RNA Interference" was a major or minor topic of these publication.
Bar chart showing 1867 publications over 16 distinct years, with a maximum of 184 publications in 2013
To see the data from this visualization as text, click here.