"Pyruvaldehyde" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
Concept/Terms
Pyruvaldehyde- Pyruvaldehyde
- Pyruvic Aldehyde
- Aldehyde, Pyruvic
- Acetylformaldehyde
- Methylglyoxal
Below are MeSH descriptors whose meaning is more general than "Pyruvaldehyde".
Below are MeSH descriptors whose meaning is more specific than "Pyruvaldehyde".
This graph shows the total number of publications written about "Pyruvaldehyde" by people in Harvard Catalyst Profiles by year, and whether "Pyruvaldehyde" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2019 | 2 | 1 | 3 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
Below are the most recent publications written about "Pyruvaldehyde" by people in Profiles.
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Methylglyoxal Drives a Distinct, Nonclassical Macrophage Activation Status. Thromb Haemost. 2021 Nov; 121(11):1464-1475.
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An Unrecognized Hazard in E-Cigarette Vapor: Preliminary Quantification of Methylglyoxal Formation from Propylene Glycol in E-Cigarettes. Int J Environ Res Public Health. 2021 01 06; 18(2).
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Association of the 1q25 Diabetes-Specific Coronary Heart Disease Locus With Alterations of the ?-Glutamyl Cycle and Increased Methylglyoxal Levels in Endothelial Cells. Diabetes. 2020 10; 69(10):2206-2216.
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Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal. Nat Immunol. 2020 05; 21(5):555-566.
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Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab. Cell Rep. 2020 02 04; 30(5):1400-1416.e6.
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Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer. Nat Commun. 2019 12 06; 10(1):5604.
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Non-enzymatic Lysine Lactoylation of Glycolytic Enzymes. Cell Chem Biol. 2020 02 20; 27(2):206-213.e6.
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Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer. Breast Cancer Res. 2019 01 23; 21(1):11.
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Methylglyoxal, a potent inducer of AGEs, connects between diabetes and cancer. Diabetes Res Clin Pract. 2019 Feb; 148:200-211.
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Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks. Proc Natl Acad Sci U S A. 2018 09 11; 115(37):9228-9233.