 Pyrones
"Pyrones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Keto-pyrans.
| Descriptor ID |
D011753
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| MeSH Number(s) |
D03.383.663.718 D03.830.718
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyrones".
Below are MeSH descriptors whose meaning is more specific than "Pyrones".
This graph shows the total number of publications written about "Pyrones" by people in Harvard Catalyst Profiles by year, and whether "Pyrones" was a major or minor topic of these publication.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 1994 | 0 | 1 | 1 | | 1995 | 2 | 0 | 2 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 2000 | 2 | 0 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 2 | 0 | 2 | | 2006 | 5 | 0 | 5 | | 2007 | 1 | 1 | 2 | | 2008 | 1 | 2 | 3 | | 2010 | 3 | 1 | 4 | | 2014 | 1 | 2 | 3 | | 2015 | 2 | 0 | 2 | | 2017 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Pyrones" by people in Profiles.
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Bouthillette LM, Darcey CA, Handy TE, Seaton SC, Wolfe AL. Isolation of the antibiotic pseudopyronine B and SAR evaluation of C3/C6 alkyl analogs. Bioorg Med Chem Lett. 2017 Jun 15; 27(12):2762-2765.
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Xia S, Lin R, Jin L, Zhao L, Kang HB, Pan Y, Liu S, Qian G, Qian Z, Konstantakou E, Zhang B, Dong JT, Chung YR, Abdel-Wahab O, Merghoub T, Zhou L, Kudchadkar RR, Lawson DH, Khoury HJ, Khuri FR, Boise LH, Lonial S, Lee BH, Pollack BP, Arbiser JL, Fan J, Lei QY, Chen J. Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth. Cell Metab. 2017 Feb 07; 25(2):358-373.
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Tian X, Lara H, Wagner KT, Saripalli S, Hyder SN, Foote M, Sethi M, Wang E, Caster JM, Zhang L, Wang AZ. Improving DNA double-strand repair inhibitor KU55933 therapeutic index in cancer radiotherapy using nanoparticle drug delivery. Nanoscale. 2015 Dec 21; 7(47):20211-9.
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Dütting S, Heidenreich J, Cherpokova D, Amin E, Zhang SC, Ahmadian MR, Brakebusch C, Nieswandt B. Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets. J Thromb Haemost. 2015 May; 13(5):827-38.
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Stavrou EX, Fang C, Merkulova A, Alhalabi O, Grobe N, Antoniak S, Mackman N, Schmaier AH. Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor. Blood. 2015 Jan 22; 125(4):710-9.
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Kim DE, Kim B, Shin HS, Kwon HJ, Park ES. The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3ß and ERK1/2 signaling pathway. Exp Cell Res. 2014 Oct 01; 327(2):264-75.
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Sheng R, Zhang TT, Felice VD, Qin T, Qin ZH, Smith CD, Sapp E, Difiglia M, Waeber C. Preconditioning stimuli induce autophagy via sphingosine kinase 2 in mouse cortical neurons. J Biol Chem. 2014 Jul 25; 289(30):20845-57.
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Wyche TP, Standiford M, Hou Y, Braun D, Johnson DA, Johnson JA, Bugni TS. Activation of the nuclear factor E2-related factor 2 pathway by novel natural products halomadurones A-D and a synthetic analogue. Mar Drugs. 2013 Dec 16; 11(12):5089-99.
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Sowd GA, Li NY, Fanning E. ATM and ATR activities maintain replication fork integrity during SV40 chromatin replication. PLoS Pathog. 2013; 9(4):e1003283.
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Batey MA, Zhao Y, Kyle S, Richardson C, Slade A, Martin NM, Lau A, Newell DR, Curtin NJ. Preclinical evaluation of a novel ATM inhibitor, KU59403, in vitro and in vivo in p53 functional and dysfunctional models of human cancer. Mol Cancer Ther. 2013 Jun; 12(6):959-67.
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