Pyrimidine Dimers

"Pyrimidine Dimers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Dimers found in DNA chains damaged by ULTRAVIOLET RAYS. They consist of two adjacent PYRIMIDINE NUCLEOTIDES, usually THYMINE nucleotides, in which the pyrimidine residues are covalently joined by a cyclobutane ring. These dimers block DNA REPLICATION.

Descriptor ID

D011740

MeSH Number(s)

D03.383.742.686.600

D13.695.578.424.600

D13.695.740.600

Concept/Terms

Pyrimidine Dimers

Thymine-Cyclobutane Dimer

Cytosine-Thymine Dimers

Below are MeSH descriptors whose meaning is more general than "Pyrimidine Dimers".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Pyrimidines [D03.383.742]
Pyrimidine Nucleotides [D03.383.742.686]
Pyrimidine Dimers [D03.383.742.686.600]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleotides [D13.695]
Polynucleotides [D13.695.578]
Oligonucleotides [D13.695.578.424]
Pyrimidine Dimers [D13.695.578.424.600]
Pyrimidine Nucleotides [D13.695.740]
Pyrimidine Dimers [D13.695.740.600]

Below are MeSH descriptors whose meaning is related to "Pyrimidine Dimers".

Below are MeSH descriptors whose meaning is more specific than "Pyrimidine Dimers".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Pyrimidine Dimers" by people in Harvard Catalyst Profiles by year, and whether "Pyrimidine Dimers" was a major or minor topic of these publication.

Bar chart showing 11 publications over 9 distinct years, with a maximum of 2 publications in 2006 and 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
2006	0	2	2
2007	0	2	2
2009	0	1	1
2011	1	0	1
2014	0	1	1
2018	0	1	1
2019	1	0	1
2020	1	0	1

Below are the most recent publications written about "Pyrimidine Dimers" by people in Profiles.

?H2AX in the S Phase after UV Irradiation Corresponds to DNA Replication and Does Not Report on the Extent of DNA Damage. Mol Cell Biol. 2020 09 28; 40(20).

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Single-molecule visualization reveals the damage search mechanism for the human NER protein XPC-RAD23B. Nucleic Acids Res. 2019 09 19; 47(16):8337-8347.

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Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche. Nature. 2018 06; 558(7710):445-448.

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AGS, SLE, and RNASEH2 mutations: translating insights into therapeutic advances. J Clin Invest. 2015 Jan; 125(1):102-4.

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High resolution mapping of modified DNA nucleobases using excision repair enzymes. Genome Res. 2014 Sep; 24(9):1534-42.

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Monitoring repair of UV-induced 6-4-photoproducts with a purified DDB2 protein complex. PLoS One. 2014; 9(1):e85896.

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Steering supramolecular patterns by nucleobase-terminated molecules. Chem Commun (Camb). 2013 Jan 18; 49(5):508-10.

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Differences in dinucleotide frequencies of thermophilic genes encoding water soluble and membrane proteins. J Zhejiang Univ Sci B. 2011 Jun; 12(6):419-27.

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Role of the ubiquitin-binding domain of Pol? in Rad18-independent translesion DNA synthesis in human cell extracts. Nucleic Acids Res. 2010 Oct; 38(19):6456-65.

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Differential effects of low-dose and high-dose beta-carotene supplementation on the signs of photoaging and type I procollagen gene expression in human skin in vivo. Dermatology. 2010; 221(2):160-71.

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