Pyridoxal Phosphate

"Pyridoxal Phosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).

Descriptor ID

D011732

MeSH Number(s)

D03.383.725.676.925.500.500

D08.211.740

Concept/Terms

Pyridoxal Phosphate

Below are MeSH descriptors whose meaning is more general than "Pyridoxal Phosphate".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Pyridines [D03.383.725]
Picolines [D03.383.725.676]
Vitamin B 6 [D03.383.725.676.925]
Pyridoxal [D03.383.725.676.925.500]
Pyridoxal Phosphate [D03.383.725.676.925.500.500]
Enzymes and Coenzymes [D08]
Coenzymes [D08.211]
Pyridoxal Phosphate [D08.211.740]

Below are MeSH descriptors whose meaning is related to "Pyridoxal Phosphate".

Below are MeSH descriptors whose meaning is more specific than "Pyridoxal Phosphate".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Pyridoxal Phosphate" by people in Harvard Catalyst Profiles by year, and whether "Pyridoxal Phosphate" was a major or minor topic of these publication.

Bar chart showing 69 publications over 26 distinct years, with a maximum of 6 publications in 2002 and 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	2	3
1996	1	2	3
1997	2	1	3
1998	2	2	4
1999	0	2	2
2000	1	0	1
2001	2	0	2
2002	5	1	6
2003	1	1	2
2004	1	3	4
2005	1	5	6
2006	0	1	1
2007	1	2	3
2009	2	3	5
2010	0	1	1
2011	1	0	1
2012	1	0	1
2013	0	3	3
2014	1	0	1
2015	0	2	2
2016	0	1	1
2017	1	3	4
2018	1	2	3
2019	2	1	3
2021	1	0	1
2022	0	3	3

Below are the most recent publications written about "Pyridoxal Phosphate" by people in Profiles.

Increased vitamin B6 turnover is associated with greater mortality risk in the general US population: A prospective biomarker study. Clin Nutr. 2022 06; 41(6):1343-1356.

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Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase. J Am Chem Soc. 2022 03 30; 144(12):5629-5642.

View in: PubMed
Vitamin B6 Metabolism Determines T Cell Anti-Tumor Responses. Front Immunol. 2022; 13:837669.

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Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB. Protein Sci. 2021 09; 30(9):1904-1918.

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5-Aminolevulinate synthase catalysis: The catcher in heme biosynthesis. Mol Genet Metab. 2019 11; 128(3):178-189.

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PLPHP deficiency: clinical, genetic, biochemical, and mechanistic insights. Brain. 2019 03 01; 142(3):542-559.

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Plasma B-vitamin and one-carbon metabolites and risk of breast cancer before and after folic acid fortification in the United States. Int J Cancer. 2019 04 15; 144(8):1929-1940.

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Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity. Cell Metab. 2018 Jun 05; 27(6):1263-1280.e6.

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Crystal Structures of Cystathionine ß-Synthase from Saccharomyces cerevisiae: One Enzymatic Step at a Time. Biochemistry. 2018 06 05; 57(22):3134-3145.

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Identification of pyridoxal phosphate-modified proteins using mass spectrometry. Rapid Commun Mass Spectrom. 2018 Feb 15; 32(3):195-200.

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