Proto-Oncogenes

"Proto-Oncogenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Normal cellular genes homologous to viral oncogenes. The products of proto-oncogenes are important regulators of biological processes and appear to be involved in the events that serve to maintain the ordered procession through the cell cycle. Proto-oncogenes have names of the form c-onc.

Descriptor ID

D011519

MeSH Number(s)

G05.360.340.024.340.375.500.791

Concept/Terms

Proto-Oncogenes

Below are MeSH descriptors whose meaning is more general than "Proto-Oncogenes".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Genes [G05.360.340.024.340]
Genes, Neoplasm [G05.360.340.024.340.375]
Oncogenes [G05.360.340.024.340.375.500]
Proto-Oncogenes [G05.360.340.024.340.375.500.791]

Below are MeSH descriptors whose meaning is related to "Proto-Oncogenes".

Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogenes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Proto-Oncogenes" by people in Harvard Catalyst Profiles by year, and whether "Proto-Oncogenes" was a major or minor topic of these publication.

Bar chart showing 162 publications over 30 distinct years, with a maximum of 21 publications in 1991

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1991	15	6	21
1992	6	5	11
1993	11	5	16
1994	7	9	16
1995	2	2	4
1996	8	1	9
1997	5	3	8
1998	3	1	4
1999	1	1	2
2000	0	2	2
2001	3	0	3
2002	6	1	7
2003	12	3	15
2004	3	2	5
2005	3	1	4
2006	1	2	3
2007	1	2	3
2008	1	4	5
2009	0	2	2
2010	1	2	3
2011	1	1	2
2012	1	2	3
2013	2	1	3
2014	1	1	2
2015	0	1	1
2016	2	0	2
2017	1	0	1
2018	0	2	2
2019	1	1	2
2021	0	1	1

Below are the most recent publications written about "Proto-Oncogenes" by people in Profiles.

Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans. Nat Commun. 2021 03 12; 12(1):1622.

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Intragenic antagonistic roles of protein and circRNA in tumorigenesis. Cell Res. 2019 08; 29(8):628-640.

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Mouse Models as a Tool for Understanding Progression in BrafV600E-Driven Thyroid Cancers. Endocrinol Metab (Seoul). 2019 03; 34(1):11-22.

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Immunohistochemistry in Anaplastic Lymphoma Kinase and Proto-Oncogene Tyrosine-Protein Kinase ROS. Arch Pathol Lab Med. 2018 07; 142(7):792-793.

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Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology. J Mol Diagn. 2018 03; 20(2):129-159.

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Downsizing Proto-oncogene cFos to Short Helix-Constrained Peptides That Bind Jun. ACS Chem Biol. 2017 08 18; 12(8):2051-2061.

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The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia. Nat Med. 2017 Mar; 23(3):301-313.

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Evi1 regulates Notch activation to induce zebrafish hematopoietic stem cell emergence. EMBO J. 2016 11 02; 35(21):2315-2331.

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CANCER. The oncogene makes its escape. Science. 2016 Mar 25; 351(6280):1398-9.

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Melanocytic nevi excised during B-Raf proto-oncogene (BRAF) inhibitor therapy: A study of 19 lesions from 10 patients. J Am Acad Dermatol. 2015 Sep; 73(3):491-9.e2.

View in: PubMed

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