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Protein Kinase C-alpha

"Protein Kinase C-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A cytoplasmic serine threonine kinase involved in regulating CELL DIFFERENTIATION and CELLULAR PROLIFERATION. Overexpression of this enzyme has been shown to promote PHOSPHORYLATION of BCL-2 PROTO-ONCOGENE PROTEINS and chemoresistance in human acute leukemia cells.

This graph shows the total number of publications written about "Protein Kinase C-alpha" by people in Harvard Catalyst Profiles by year, and whether "Protein Kinase C-alpha" was a major or minor topic of these publication.
Bar chart showing 87 publications over 25 distinct years, with a maximum of 9 publications in 2006
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.