Harvard Catalyst Profiles

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Protein Kinase C

"Protein Kinase C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.


This graph shows the total number of publications written about "Protein Kinase C" by people in Harvard Catalyst Profiles by year, and whether "Protein Kinase C" was a major or minor topic of these publication.
Bar chart showing 1031 publications over 31 distinct years, with a maximum of 60 publications in 1998
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.