Harvard Catalyst Profiles

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Protein Footprinting

"Protein Footprinting" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A method for determining points of contact between interacting proteins or binding sites of proteins to nucleic acids. Protein footprinting utilizes a protein cutting reagent or protease. Protein cleavage is inhibited where the proteins, or nucleic acids and protein, contact each other. After completion of the cutting reaction, the remaining peptide fragments are analyzed by electrophoresis.


This graph shows the total number of publications written about "Protein Footprinting" by people in Harvard Catalyst Profiles by year, and whether "Protein Footprinting" was a major or minor topic of these publication.
Bar chart showing 8 publications over 6 distinct years, with a maximum of 2 publications in 2002 and 2014
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.