Harvard Catalyst Profiles

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Proliferating Cell Nuclear Antigen

"Proliferating Cell Nuclear Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.


This graph shows the total number of publications written about "Proliferating Cell Nuclear Antigen" by people in Harvard Catalyst Profiles by year, and whether "Proliferating Cell Nuclear Antigen" was a major or minor topic of these publication.
Bar chart showing 225 publications over 30 distinct years, with a maximum of 14 publications in 2011
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.