Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Prions

"Prions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.


This graph shows the total number of publications written about "Prions" by people in Harvard Catalyst Profiles by year, and whether "Prions" was a major or minor topic of these publication.
Bar chart showing 227 publications over 26 distinct years, with a maximum of 20 publications in 2014
To see the data from this visualization as text, click here.
Related Networks
People
Explore
_
Similar Concepts
_
Top Journals 
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.