Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Presenilin-2

"Presenilin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Integral membrane protein of Golgi and endoplasmic reticulum. Its homodimer is an essential component of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PEPTIDES precursors. PSEN2 mutations cause ALZHEIMER DISEASE type 4.


This graph shows the total number of publications written about "Presenilin-2" by people in Harvard Catalyst Profiles by year, and whether "Presenilin-2" was a major or minor topic of these publication.
Bar chart showing 84 publications over 23 distinct years, with a maximum of 11 publications in 2000
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.