Polymorphism, Single-Stranded Conformational
"Polymorphism, Single-Stranded Conformational" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
Concept/Terms
Polymorphism, Single-Stranded Conformational- Polymorphism, Single-Stranded Conformational
- Polymorphism, Single Stranded Conformational
- SSCP
- Single-Stranded Conformational Polymorphism
- Conformational Polymorphism, Single-Stranded
- Conformational Polymorphisms, Single-Stranded
- Polymorphisms, Single-Stranded Conformational
- Single Stranded Conformational Polymorphism
- Single-Stranded Conformational Polymorphisms
Below are MeSH descriptors whose meaning is more general than "Polymorphism, Single-Stranded Conformational".
Below are MeSH descriptors whose meaning is more specific than "Polymorphism, Single-Stranded Conformational".
This graph shows the total number of publications written about "Polymorphism, Single-Stranded Conformational" by people in Harvard Catalyst Profiles by year, and whether "Polymorphism, Single-Stranded Conformational" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 4 | 4 |
| 1995 | 2 | 17 | 19 |
| 1996 | 0 | 26 | 26 |
| 1997 | 0 | 27 | 27 |
| 1998 | 2 | 22 | 24 |
| 1999 | 4 | 30 | 34 |
| 2000 | 0 | 21 | 21 |
| 2001 | 1 | 29 | 30 |
| 2002 | 2 | 16 | 18 |
| 2003 | 1 | 11 | 12 |
| 2004 | 0 | 10 | 10 |
| 2005 | 1 | 4 | 5 |
| 2006 | 1 | 3 | 4 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
Below are the most recent publications written about "Polymorphism, Single-Stranded Conformational" by people in Profiles.
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A three-gene model to robustly identify breast cancer molecular subtypes. J Natl Cancer Inst. 2012 Feb 22; 104(4):311-25.
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Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population. Gene. 2011 Nov 01; 487(1):10-20.
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Arachidonic acid ?-hydroxylase CYP4A11: inter-ethnic variations in the 8590T>C loss-of-function variant. Mol Biol Rep. 2012 Feb; 39(2):1503-8.
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Genetic polymorphisms of glycine N-acyltransferase (GLYAT) in a French Caucasian population. Xenobiotica. 2010 Dec; 40(12):853-61.
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Two types of C/EBPa mutations play distinct but collaborative roles in leukemogenesis: lessons from clinical data and BMT models. Blood. 2011 Jan 06; 117(1):221-33.
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A screen of SLC1A1 for OCD-related alleles. Am J Med Genet B Neuropsychiatr Genet. 2010 Mar 05; 153B(2):675-679.
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Diverse MHC IIB allele repertoire increases parasite resistance and body condition in the Long-tailed giant rat (Leopoldamys sabanus). BMC Evol Biol. 2009 Nov 23; 9:269.
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Mutation analysis of Rad18 in human cancer cell lines and non small cell lung cancer tissues. J Exp Clin Cancer Res. 2009 Jul 25; 28:106.
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Use of formalin-fixed paraffin-embedded tissue and single-strand conformation polymorphism analysis for polymerase chain reaction of antigen receptor rearrangements in dogs. J Vet Med Sci. 2009 Apr; 71(4):535-8.
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EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset. Mod Pathol. 2009 Apr; 22(4):508-15.