Polyendocrinopathies, Autoimmune
"Polyendocrinopathies, Autoimmune" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
Concept/Terms
Polyglandular Type III Autoimmune Syndrome- Polyglandular Type III Autoimmune Syndrome
- Polyglandular Autoimmune Syndrome, Type 3
- Autoimmune Syndrome Type III, Polyglandular
- Autoimmune Polyglandular Syndrome Type III
- Autoimmune Polyglandular Syndrome, Type 3
Polyglandular Type I Autoimmune Syndrome- Polyglandular Type I Autoimmune Syndrome
- Polyglandular Autoimmune Syndrome, Type 1
- Autoimmune Polyglandular Syndrome, Type 1
- Autoimmune Syndrome Type I, Polyglandular
- Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy
- Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy
- Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophies
- Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophies, Autoimmune
- Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy, Autoimmune
- Autoimmune Polyglandular Syndrome Type I
Polyglandular Type II Autoimmune Syndrome- Polyglandular Type II Autoimmune Syndrome
- Autoimmune Syndrome Type II, Polyglandular
- Schmidt's Syndrome
- Schmidt Syndrome
- Schmidts Syndrome
- Syndrome, Schmidt's
- Polyglandular Deficiency Syndrome, Type 2
- Autoimmune Polyendocrine Syndrome, Type 2
- Multiple Endocrine Deficiency Syndrome, Type 2
- Polyglandular Autoimmune Syndrome, Type 2
- Autoimmune Polyglandular Syndrome Type II
- Diabetes Mellitus, Addison's Disease, Myxedema
Below are MeSH descriptors whose meaning is more general than "Polyendocrinopathies, Autoimmune".
Below are MeSH descriptors whose meaning is more specific than "Polyendocrinopathies, Autoimmune".
This graph shows the total number of publications written about "Polyendocrinopathies, Autoimmune" by people in Harvard Catalyst Profiles by year, and whether "Polyendocrinopathies, Autoimmune" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2007 | 3 | 0 | 3 |
| 2008 | 2 | 0 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 3 | 0 | 3 |
| 2022 | 4 | 0 | 4 |
Below are the most recent publications written about "Polyendocrinopathies, Autoimmune" by people in Profiles.
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Case 29-2022: A 33-Year-Old Man with Chronic Diarrhea and Autoimmune Enteropathy. N Engl J Med. 2022 09 22; 387(12):1124-1134.
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Revisiting Genetic Testing for Patients with Negative Results: IPEX and FOXP3. J Clin Immunol. 2022 08; 42(6):1164-1167.
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A Case Report of Fatal Mucormycosis in a 30-Year-Old Patient with Autoimmune Polyendocrine Syndrome Type 1. J Clin Immunol. 2022 05; 42(4):863-865.
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Pathogenic TNF-a drives peripheral nerve inflammation in an Aire-deficient model of autoimmunity. Proc Natl Acad Sci U S A. 2022 01 25; 119(4).
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Antibody responses to the SARS-CoV-2 vaccine in individuals with various inborn errors of immunity. J Allergy Clin Immunol. 2021 11; 148(5):1192-1197.
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Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1. J Exp Med. 2021 07 05; 218(7).
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Cytokine-specific autoantibodies shape the gut microbiome in autoimmune polyendocrine syndrome type 1. J Allergy Clin Immunol. 2021 09; 148(3):876-888.
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Aberrant type 1 immunity drives susceptibility to mucosal fungal infections. Science. 2021 01 15; 371(6526).
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Dual functions of Aire CARD multimerization in the transcriptional regulation of T cell tolerance. Nat Commun. 2020 04 02; 11(1):1625.
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[Hypophysitis and retroperitoneal fibrosis associated with autoimmune polyglandular syndrome and IgG4-related disease. Report of one case]. Rev Med Chil. 2018 Dec; 146(12):1486-1492.