Harvard Catalyst Profiles

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Picrotoxin

"Picrotoxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates.


This graph shows the total number of publications written about "Picrotoxin" by people in Harvard Catalyst Profiles by year, and whether "Picrotoxin" was a major or minor topic of these publication.
Bar chart showing 41 publications over 22 distinct years, with a maximum of 5 publications in 2004
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.