Phosphopyruvate Hydratase

"Phosphopyruvate Hydratase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A hydro-lyase that catalyzes the dehydration of 2-phosphoglycerate to form PHOSPHOENOLPYRUVATE. Several different isoforms of this enzyme exist, each with its own tissue specificity.

Descriptor ID

D010751

MeSH Number(s)

D08.811.520.241.300.500

Concept/Terms

Phosphopyruvate Hydratase

beta-Enolase

gamma-Enolase

alpha-Enolase

Below are MeSH descriptors whose meaning is more general than "Phosphopyruvate Hydratase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Lyases [D08.811.520]
Carbon-Oxygen Lyases [D08.811.520.241]
Hydro-Lyases [D08.811.520.241.300]
Phosphopyruvate Hydratase [D08.811.520.241.300.500]

Below are MeSH descriptors whose meaning is related to "Phosphopyruvate Hydratase".

Below are MeSH descriptors whose meaning is more specific than "Phosphopyruvate Hydratase".

Phosphopyruvate Hydratase
tau-Crystallins

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Phosphopyruvate Hydratase" by people in Harvard Catalyst Profiles by year, and whether "Phosphopyruvate Hydratase" was a major or minor topic of these publication.

Bar chart showing 88 publications over 28 distinct years, with a maximum of 9 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1991	0	4	4
1992	2	1	3
1993	1	0	1
1994	0	5	5
1996	0	1	1
1997	0	2	2
1998	1	0	1
1999	1	1	2
2001	0	1	1
2002	1	2	3
2003	0	5	5
2004	0	5	5
2005	0	5	5
2006	1	2	3
2007	0	2	2
2008	0	6	6
2009	3	3	6
2010	0	5	5
2011	0	3	3
2012	2	7	9
2013	2	1	3
2014	0	2	2
2015	0	3	3
2016	1	1	2
2017	0	2	2
2018	0	1	1
2019	0	1	1
2020	2	0	2

Below are the most recent publications written about "Phosphopyruvate Hydratase" by people in Profiles.

An enolase inhibitor for the targeted treatment of ENO1-deleted cancers. Nat Metab. 2020 12; 2(12):1413-1426.

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Preclinical validation of Alpha-Enolase (ENO1) as a novel immunometabolic target in multiple myeloma. Oncogene. 2020 03; 39(13):2786-2796.

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Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate. Sci Rep. 2019 11 19; 9(1):17106.

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?FosB Requires Galanin, but not Leptin, to Increase Bone Mass via the Hypothalamus, but both are needed to increase Energy expenditure. J Bone Miner Res. 2019 09; 34(9):1707-1720.

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Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens. Biochemistry. 2019 03 05; 58(9):1188-1197.

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An on demand macaque model of mesial temporal lobe seizures induced by unilateral intra hippocampal injection of penicillin. Epilepsy Res. 2018 05; 142:20-28.

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Multimodal Outcome Prognostication After Cardiac Arrest and Targeted Temperature Management: Analysis at 36 °C. Neurocrit Care. 2018 02; 28(1):104-109.

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a-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration. Neurobiol Dis. 2017 Sep; 105:84-98.

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Neuron-specific enolase levels as a marker for possible neuronal damage in idiopathic intracranial hypertension. Acta Neurol Belg. 2017 Sep; 117(3):707-711.

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Humoral immune responses toward tumor-derived antigens in previously untreated patients with chronic lymphocytic leukemia. Oncotarget. 2017 Jan 10; 8(2):3274-3288.

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