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Phosphatidylinositol Diacylglycerol-Lyase

"Phosphatidylinositol Diacylglycerol-Lyase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A phosphorus-oxygen lyase found primarily in BACTERIA. The enzyme catalyzes the cleavage of a phosphoester linkage in 1-phosphatidyl-1D-myo-inositol to form 1D-myo-inositol 1,2-cyclic phosphate and diacylglycerol. The enzyme was formerly classified as a phosphoric diester hydrolase (EC 3.1.4.10) and is often referred to as a TYPE C PHOSPHOLIPASES. However it is now known that a cyclic phosphate is the final product of this enzyme and that water does not enter into the reaction.


This graph shows the total number of publications written about "Phosphatidylinositol Diacylglycerol-Lyase" by people in Harvard Catalyst Profiles by year, and whether "Phosphatidylinositol Diacylglycerol-Lyase" was a major or minor topic of these publication.
Bar chart showing 17 publications over 11 distinct years, with a maximum of 3 publications in 1994 and 1998
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.