Paraparesis, Tropical Spastic
"Paraparesis, Tropical Spastic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by HUMAN T-CELL LEUKEMIA VIRUS I. Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239)
MeSH Number(s)
C02.182.600.600
C02.782.815.200.470.710
C10.228.228.210.575.500
C10.228.228.618.700
C10.228.854.525.700
Concept/Terms
Paraparesis, Tropical Spastic- Paraparesis, Tropical Spastic
- HTLV-I-Associated Myelopathy
- HTLV I Associated Myelopathy
- HTLV-I-Associated Myelopathies
- Myelopathies, HTLV-I-Associated
- Myelopathy, HTLV-I-Associated
- HTLV-I-Associated Myelopathy-Tropical Spastic Paraparesis
- HTLV I Associated Myelopathy Tropical Spastic Paraparesis
- Tropical Spastic Paraparesis
- Parapareses, Tropical Spastic
- Spastic Parapareses, Tropical
- Spastic Paraparesis, Tropical
- Tropical Spastic Parapareses
- Myelopathies, HTLV I Associated
- Myelopathy, Human T-Lymphotropic Virus Type 1 Associated
- Myelopathy, Human T Lymphotropic Virus Type 1 Associated
- Paraplegia, Tropical Spastic
- Paraplegias, Tropical Spastic
- Spastic Paraplegia, Tropical
- Spastic Paraplegias, Tropical
- Tropical Spastic Paraplegia
- Tropical Spastic Paraplegias
- HTLV I Associated Myelopathies
- Human T-Lymphotropic Virus Type 1 Associated Myelopathy
- Human T Lymphotropic Virus Type 1 Associated Myelopathy
Below are MeSH descriptors whose meaning is more general than "Paraparesis, Tropical Spastic".
Below are MeSH descriptors whose meaning is more specific than "Paraparesis, Tropical Spastic".
This graph shows the total number of publications written about "Paraparesis, Tropical Spastic" by people in Harvard Catalyst Profiles by year, and whether "Paraparesis, Tropical Spastic" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 1 | 0 | 1 |
| 1995 | 2 | 0 | 2 |
| 1997 | 0 | 1 | 1 |
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2014 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
Below are the most recent publications written about "Paraparesis, Tropical Spastic" by people in Profiles.
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Effectiveness and safety of non-tumor necrosis factor inhibitor therapy for anti-human T-cell leukemia virus type 1 antibody-positive rheumatoid arthritis. Mod Rheumatol. 2021 Sep; 31(5):972-978.
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Brief Report: Attenuated Effectiveness of Tumor Necrosis Factor Inhibitors for Anti-Human T Lymphotropic Virus Type I Antibody-Positive Rheumatoid Arthritis. Arthritis Rheumatol. 2018 07; 70(7):1014-1021.
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Tumor necrosis factor alpha inhibitors have no effect on a human T-lymphotropic virus type-I (HTLV-I)-infected cell line from patients with HTLV-I-associated myelopathy. BMC Immunol. 2017 02 03; 18(1):7.
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Human T-lymphotropic virus type-I (HTLV-I)-associated myelopathy with bulbar palsy-type amyotrophic lateral sclerosis-like symptoms. Intern Med. 2015; 54(9):1105-7.
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Atrophy, focal spinal cord lesions and alterations of diffusion tensor imaging (DTI) parameters in asymptomatic virus carriers and patients suffering from human T-lymphotrophic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP). J Neurovirol. 2014 Dec; 20(6):583-90.
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Digital droplet PCR (ddPCR) for the precise quantification of human T-lymphotropic virus 1 proviral loads in peripheral blood and cerebrospinal fluid of HAM/TSP patients and identification of viral mutations. J Neurovirol. 2014 Aug; 20(4):341-51.
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Immunopathogenesis and neurological manifestations associated to HTLV-1 infection. Rev Soc Bras Med Trop. 2012 Oct; 45(5):545-52.
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Aquaporin-4 antibodies are not related to HTLV-1 associated myelopathy. PLoS One. 2012; 7(7):e39372.
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HAM/TSP: association between white matter lesions on magnetic resonance imaging, clinical and cerebrospinal fluid findings. Arq Neuropsiquiatr. 2012 Apr; 70(4):246-51.
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Cerebrospinal fluid neopterin, but not osteopontin, is a valuable biomarker for the treatment response in patients with HTLV-I-associated myelopathy. Intern Med. 2013; 52(19):2203-8.