Harvard Catalyst Profiles

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PDZ Domains

"PDZ Domains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Protein interaction domains of about 70-90 amino acid residues, named after a common structure found in PSD-95, Discs Large, and Zona Occludens 1 proteins. PDZ domains are involved in the recruitment and interaction of proteins, and aid the formation of protein scaffolds and signaling networks. This is achieved by sequence-specific binding between a PDZ domain in one protein and a PDZ motif in another protein.


This graph shows the total number of publications written about "PDZ Domains" by people in Harvard Catalyst Profiles by year, and whether "PDZ Domains" was a major or minor topic of these publication.
Bar chart showing 20 publications over 9 distinct years, with a maximum of 4 publications in 2008 and 2009 and 2013
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.