Harvard Catalyst Profiles

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Osteoprotegerin

"Osteoprotegerin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.


This graph shows the total number of publications written about "Osteoprotegerin" by people in Harvard Catalyst Profiles by year, and whether "Osteoprotegerin" was a major or minor topic of these publication.
Bar chart showing 128 publications over 23 distinct years, with a maximum of 11 publications in 2013
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.