Harvard Catalyst Profiles

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Osteocalcin

"Osteocalcin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic acid (Gla), which, in the presence of CALCIUM, promotes binding to HYDROXYAPATITE and subsequent accumulation in BONE MATRIX.


This graph shows the total number of publications written about "Osteocalcin" by people in Harvard Catalyst Profiles by year, and whether "Osteocalcin" was a major or minor topic of these publication.
Bar chart showing 182 publications over 31 distinct years, with a maximum of 12 publications in 2008
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.