"Oncogenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
MeSH Number(s)
G05.360.340.024.340.375.500
Concept/Terms
Oncogenes- Oncogenes
- Transforming Genes
- Transforming Gene
- Gene, Transforming
- Genes, Transforming
- Oncogene
Below are MeSH descriptors whose meaning is more general than "Oncogenes".
Below are MeSH descriptors whose meaning is more specific than "Oncogenes".
This graph shows the total number of publications written about "Oncogenes" by people in Harvard Catalyst Profiles by year, and whether "Oncogenes" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 11 | 4 | 15 |
| 1994 | 4 | 11 | 15 |
| 1995 | 8 | 6 | 14 |
| 1996 | 6 | 6 | 12 |
| 1997 | 5 | 4 | 9 |
| 1998 | 5 | 4 | 9 |
| 1999 | 6 | 3 | 9 |
| 2000 | 1 | 5 | 6 |
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 1 | 3 |
| 2003 | 7 | 7 | 14 |
| 2004 | 5 | 5 | 10 |
| 2005 | 2 | 5 | 7 |
| 2006 | 10 | 7 | 17 |
| 2007 | 8 | 9 | 17 |
| 2008 | 8 | 6 | 14 |
| 2009 | 14 | 5 | 19 |
| 2010 | 11 | 6 | 17 |
| 2011 | 10 | 14 | 24 |
| 2012 | 18 | 10 | 28 |
| 2013 | 10 | 18 | 28 |
| 2014 | 11 | 15 | 26 |
| 2015 | 6 | 5 | 11 |
| 2016 | 8 | 11 | 19 |
| 2017 | 13 | 11 | 24 |
| 2018 | 14 | 16 | 30 |
| 2019 | 12 | 9 | 21 |
| 2020 | 10 | 16 | 26 |
| 2021 | 9 | 21 | 30 |
| 2022 | 9 | 15 | 24 |
| 2023 | 0 | 2 | 2 |
Below are the most recent publications written about "Oncogenes" by people in Profiles.
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Epigenomic charting and functional annotation of risk loci in renal cell carcinoma. Nat Commun. 2023 Jan 21; 14(1):346.
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Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer. Cell. 2023 Jan 19; 186(2):363-381.e19.
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Single-cell RNA sequencing identifies a paracrine interaction that may drive oncogenic notch signaling in human adenoid cystic carcinoma. Cell Rep. 2022 11 29; 41(9):111743.
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Developmental Deconvolution for Classification of Cancer Origin. Cancer Discov. 2022 11 02; 12(11):2566-2585.
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Rare FGFR Oncogenic Alterations in Sequenced Pediatric Solid and Brain Tumors Suggest FGFR Is a Relevant Molecular Target in Childhood Cancer. JCO Precis Oncol. 2022 11; 6:e2200390.
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Getting a handle on KRAS inhibitor resistance with hapten-mediated anti-tumor immunity. Cancer Cell. 2022 09 12; 40(9):908-910.
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FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits. Cancer Res. 2022 09 02; 82(17):2980-3001.
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PH domain-mediated autoinhibition and oncogenic activation of Akt. Elife. 2022 08 15; 11.
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Precision Combination Therapies Based on Recurrent Oncogenic Coalterations. Cancer Discov. 2022 06 02; 12(6):1542-1559.
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Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy. N Engl J Med. 2022 05 26; 386(21):1998-2010.