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Oncogenes

"Oncogenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.


This graph shows the total number of publications written about "Oncogenes" by people in Harvard Catalyst Profiles by year, and whether "Oncogenes" was a major or minor topic of these publication.
Bar chart showing 523 publications over 31 distinct years, with a maximum of 37 publications in 2012
To see the data from this visualization as text, click here.
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