Oligomycins

"Oligomycins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A closely related group of toxic substances elaborated by various strains of Streptomyces. They are 26-membered macrolides with lactone moieties and double bonds and inhibit various ATPases, causing uncoupling of phosphorylation from mitochondrial respiration. Used as tools in cytochemistry. Some specific oligomycins are RUTAMYCIN, peliomycin, and botrycidin (formerly venturicidin X).

Descriptor ID

D009840

MeSH Number(s)

D02.540.505.620

Concept/Terms

Oligomycins

Below are MeSH descriptors whose meaning is more general than "Oligomycins".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Lactones [D02.540]
Macrolides [D02.540.505]
Oligomycins [D02.540.505.620]

Below are MeSH descriptors whose meaning is related to "Oligomycins".

Below are MeSH descriptors whose meaning is more specific than "Oligomycins".

Oligomycins
Rutamycin

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Oligomycins" by people in Harvard Catalyst Profiles by year, and whether "Oligomycins" was a major or minor topic of these publication.

Bar chart showing 11 publications over 9 distinct years, with a maximum of 2 publications in 1998 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	2	2
2003	0	1	1
2004	0	1	1
2012	0	1	1
2014	1	1	2
2015	0	1	1
2016	0	1	1
2019	0	1	1
2021	0	1	1

Below are the most recent publications written about "Oligomycins" by people in Profiles.

PGC-1a mediates a metabolic host defense response in human airway epithelium during rhinovirus infections. Nat Commun. 2021 06 16; 12(1):3669.

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Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction. Proc Natl Acad Sci U S A. 2021 Jan 26; 118(4).

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A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering. Cell. 2019 11 14; 179(5):1222-1238.e17.

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High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science. 2018 05 11; 360(6389).

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Wildtype adult stem cells, unlike tumor cells, are resistant to cellular damages in Drosophila. Dev Biol. 2016 Mar 15; 411(2):207-216.

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Adaptive aneuploidy protects against thiol peroxidase deficiency by increasing respiration via key mitochondrial proteins. Proc Natl Acad Sci U S A. 2015 Aug 25; 112(34):10685-90.

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Tyrosine kinase inhibition in leukemia induces an altered metabolic state sensitive to mitochondrial perturbations. Clin Cancer Res. 2015 Mar 15; 21(6):1360-72.

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Sites of superoxide and hydrogen peroxide production by muscle mitochondria assessed ex vivo under conditions mimicking rest and exercise. J Biol Chem. 2015 Jan 02; 290(1):209-27.

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Mitochondria distinguish granule-stored from de novo synthesized tumor necrosis factor secretion in human mast cells. Int Arch Allergy Immunol. 2012; 159(1):23-32.

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Orexin neurons as conditional glucosensors: paradoxical regulation of sugar sensing by intracellular fuels. J Physiol. 2011 Dec 01; 589(Pt 23):5701-8.

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