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profileNucleic Acid Hybridization

"Nucleic Acid Hybridization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)


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This graph shows the total number of publications written about "Nucleic Acid Hybridization" by people in Harvard Catalyst Profiles by year, and whether "Nucleic Acid Hybridization" was a major or minor topic of these publication.
Bar chart showing 1181 publications over 37 distinct years, with a maximum of 111 publications in 1988
To see the data from this visualization as text, click here.