Harvard Catalyst Profiles

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Nuclease Protection Assays

"Nuclease Protection Assays" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Techniques for measuring specific nucleic acid interaction with another nucleic acid or with a protein by digestion of the non-interacting nucleic acid by various nucleases. After all non-interacting regions are eliminated by nuclease digestion, the protected nucleic acid that remains is analyzed. DNA FOOTPRINTING utilizes this technique to analyze the DNA contact sites of DNA-BINDING PROTEINS.


This graph shows the total number of publications written about "Nuclease Protection Assays" by people in Harvard Catalyst Profiles by year, and whether "Nuclease Protection Assays" was a major or minor topic of these publication.
Bar chart showing 15 publications over 9 distinct years, with a maximum of 3 publications in 2000 and 2003
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.