Neoplastic Syndromes, Hereditary
"Neoplastic Syndromes, Hereditary" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The condition of a pattern of malignancies within a family, but not every individual's necessarily having the same neoplasm. Characteristically the tumor tends to occur at an earlier than average age, individuals may have more than one primary tumor, the tumors may be multicentric, usually more than 25 percent of the individuals in direct lineal descent from the proband are affected, and the cancer predisposition in these families behaves as an autosomal dominant trait with about 60 percent penetrance.
Concept/Terms
Neoplastic Syndromes, Hereditary- Neoplastic Syndromes, Hereditary
- Hereditary Neoplastic Syndromes
- Hereditary Neoplastic Syndrome
- Neoplastic Syndrome, Hereditary
- Syndrome, Hereditary Neoplastic
- Syndromes, Hereditary Neoplastic
- Hereditary Cancer Syndromes
- Cancer Syndrome, Hereditary
- Hereditary Cancer Syndrome
- Syndrome, Hereditary Cancer
- Syndromes, Hereditary Cancer
- Cancer Syndromes, Hereditary
Below are MeSH descriptors whose meaning is more general than "Neoplastic Syndromes, Hereditary".
Below are MeSH descriptors whose meaning is more specific than "Neoplastic Syndromes, Hereditary".
This graph shows the total number of publications written about "Neoplastic Syndromes, Hereditary" by people in Harvard Catalyst Profiles by year, and whether "Neoplastic Syndromes, Hereditary" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1995 | 2 | 0 | 2 |
| 1996 | 1 | 0 | 1 |
| 1997 | 2 | 0 | 2 |
| 1998 | 4 | 0 | 4 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 1 | 2 |
| 2002 | 1 | 0 | 1 |
| 2005 | 2 | 1 | 3 |
| 2007 | 4 | 0 | 4 |
| 2008 | 4 | 0 | 4 |
| 2009 | 1 | 2 | 3 |
| 2010 | 1 | 1 | 2 |
| 2011 | 3 | 3 | 6 |
| 2012 | 2 | 3 | 5 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 4 | 4 | 8 |
| 2016 | 3 | 3 | 6 |
| 2017 | 5 | 1 | 6 |
| 2018 | 6 | 1 | 7 |
| 2019 | 12 | 4 | 16 |
| 2020 | 6 | 1 | 7 |
| 2021 | 6 | 1 | 7 |
| 2022 | 8 | 6 | 14 |
| 2023 | 7 | 0 | 7 |
| 2024 | 2 | 0 | 2 |
Below are the most recent publications written about "Neoplastic Syndromes, Hereditary" by people in Profiles.
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Integrated analyses of the genetic and clinicopathological features of cholangiolocarcinoma: cholangiolocarcinoma may be characterized by mismatch-repair deficiency. J Pathol. 2024 May; 263(1):32-46.
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A Panel-Based Mutational Signature of Mismatch Repair Deficiency is Associated With Durable Response to Pembrolizumab in Metastatic Castration-Resistant Prostate Cancer. Clin Genitourin Cancer. 2024 Apr; 22(2):558-568.e3.
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Benchmarking mismatch repair testing for patients with cancer receiving immunotherapy. Cancer Cell. 2024 01 08; 42(1):6-7.
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Kidney cancer: Links between hereditary syndromes and sporadic tumorigenesis. Semin Diagn Pathol. 2024 Jan; 41(1):1-7.
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Dedifferentiated and Undifferentiated Ovarian Carcinoma: An Aggressive and Molecularly Distinct Ovarian Tumor Characterized by Frequent SWI/SNF Complex Inactivation. Mod Pathol. 2024 Jan; 37(1):100374.
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Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity. Nat Genet. 2023 10; 55(10):1686-1695.
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PREMM5 distinguishes sporadic from Lynch syndrome-associated MMR-deficient/MSI-high colorectal cancer. Fam Cancer. 2023 10; 22(4):459-465.
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Mismatch Repair Deficiency and Lynch Syndrome Among Adult Patients With Glioma. JCO Precis Oncol. 2023 05; 7:e2200525.
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Diseases of Hereditary Renal Cell Cancers. Urol Clin North Am. 2023 May; 50(2):205-215.
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Fumarate hydratase-deficient testicular sex cord-stromal tumour (FH-TSCST): proposal for reclassification of a subset of Leydig cell tumours with distinct molecular and clinicopathologic features. Histopathology. 2023 03; 82(4):646-647.