Neoplasms, Second Primary
"Neoplasms, Second Primary" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.
Concept/Terms
Neoplasms, Second Primary- Neoplasms, Second Primary
- Neoplasm, Second Primary
- Second Primary Neoplasm
- Metachronous Second Primary Neoplasms
- Neoplasms, Metachronous
- Second Primary Neoplasms, Metachronous
- Second Malignancy
- Malignancies, Second
- Malignancy, Second
- Second Malignancies
- Second Neoplasm
- Neoplasm, Second
- Neoplasms, Second
- Second Neoplasms
- Second Primary Neoplasms
- Metachronous Neoplasms
- Metachronous Neoplasm
- Neoplasm, Metachronous
- Neoplasms, Metachronous Second Primary
Neoplasms, Therapy-Associated- Neoplasms, Therapy-Associated
- Neoplasm, Therapy-Associated
- Neoplasms, Therapy Associated
- Therapy-Associated Neoplasm
- Neoplasms, Treatment-Associated
- Neoplasm, Treatment-Associated
- Neoplasms, Treatment Associated
- Treatment-Associated Neoplasm
- Neoplasms, Treatment-Related
- Neoplasm, Treatment-Related
- Neoplasms, Treatment Related
- Treatment-Related Neoplasm
- Therapy-Related Neoplasms
- Therapy Related Neoplasms
- Treatment-Associated Neoplasms
- Treatment Associated Neoplasms
- Treatment-Related Neoplasms
- Treatment Related Neoplasms
- Neoplasms, Therapy-Related
- Neoplasm, Therapy-Related
- Neoplasms, Therapy Related
- Therapy-Related Neoplasm
- Therapy-Associated Neoplasms
- Therapy Associated Neoplasms
Therapy-Associated Cancer- Therapy-Associated Cancer
- Cancer, Therapy-Associated
- Cancers, Therapy-Associated
- Therapy Associated Cancer
- Therapy-Associated Cancers
- Therapy-Related Cancer
- Cancer, Therapy-Related
- Cancers, Therapy-Related
- Therapy Related Cancer
- Therapy-Related Cancers
- Treatment-Related Cancer
- Cancer, Treatment-Related
- Cancers, Treatment-Related
- Treatment Related Cancer
- Treatment-Related Cancers
- Treatment-Associated Cancer
- Cancer, Treatment-Associated
- Cancers, Treatment-Associated
- Treatment Associated Cancer
- Treatment-Associated Cancers
Cancer, Second Primary- Cancer, Second Primary
- Cancers, Second Primary
- Second Primary Cancer
- Second Primary Cancers
- Second Cancer
- Cancer, Second
- Cancers, Second
- Second Cancers
Below are MeSH descriptors whose meaning is more general than "Neoplasms, Second Primary".
Below are MeSH descriptors whose meaning is more specific than "Neoplasms, Second Primary".
This graph shows the total number of publications written about "Neoplasms, Second Primary" by people in Harvard Catalyst Profiles by year, and whether "Neoplasms, Second Primary" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 9 | 1 | 10 |
| 1994 | 7 | 3 | 10 |
| 1995 | 3 | 4 | 7 |
| 1996 | 4 | 1 | 5 |
| 1997 | 7 | 4 | 11 |
| 1998 | 5 | 7 | 12 |
| 1999 | 7 | 1 | 8 |
| 2000 | 8 | 8 | 16 |
| 2001 | 9 | 3 | 12 |
| 2002 | 7 | 4 | 11 |
| 2003 | 13 | 2 | 15 |
| 2004 | 10 | 2 | 12 |
| 2005 | 15 | 6 | 21 |
| 2006 | 11 | 4 | 15 |
| 2007 | 23 | 3 | 26 |
| 2008 | 20 | 5 | 25 |
| 2009 | 17 | 5 | 22 |
| 2010 | 10 | 5 | 15 |
| 2011 | 17 | 6 | 23 |
| 2012 | 24 | 7 | 31 |
| 2013 | 11 | 2 | 13 |
| 2014 | 20 | 2 | 22 |
| 2015 | 22 | 3 | 25 |
| 2016 | 27 | 6 | 33 |
| 2017 | 24 | 4 | 28 |
| 2018 | 22 | 8 | 30 |
| 2019 | 20 | 2 | 22 |
| 2020 | 22 | 5 | 27 |
| 2021 | 16 | 5 | 21 |
| 2022 | 36 | 0 | 36 |
| 2023 | 18 | 0 | 18 |
Below are the most recent publications written about "Neoplasms, Second Primary" by people in Profiles.
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Magnetic resonance imaging accuracy in staging early and locally advanced rectal cancer. Surg Oncol. 2023 Oct; 50:101987.
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Results of an Open-label, Phase Ia/b Study of Pembrolizumab plus Olaratumab in Patients with Unresectable, Locally Advanced, or Metastatic Soft-Tissue Sarcoma. Clin Cancer Res. 2023 09 01; 29(17):3320-3328.
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Disparities in testicular cancer incidence, mortality, and place of death trends from 1999 to 2020: A comprehensive cohort study. Cancer Rep (Hoboken). 2023 10; 6(10):e1880.
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Real-world pan-cancer landscape of frameshift mutations and their role in predicting responses to immune checkpoint inhibitors in cancers with low tumor mutational burden. J Immunother Cancer. 2023 08; 11(8).
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Prognostic impact of secondary versus de novo ontogeny in acute myeloid leukemia is accounted for by the European LeukemiaNet 2022 risk classification. Leukemia. 2023 09; 37(9):1915-1918.
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Pre-diagnostic cigarette smoking and risk of second primary cancer: The Melbourne Collaborative Cohort Study. Cancer Epidemiol. 2023 08; 85:102406.
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Impact of second primary malignancy post-autologous transplantation on outcomes of multiple myeloma: a CIBMTR analysis. Blood Adv. 2023 06 27; 7(12):2746-2757.
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Intracranial Efficacy of Adagrasib in Patients From the KRYSTAL-1 Trial With KRASG12C-Mutated Non-Small-Cell Lung Cancer Who Have Untreated CNS Metastases. J Clin Oncol. 2023 10 01; 41(28):4472-4477.
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Metastatic solid tumors to the testis: a clinicopathologic evaluation of 157 cases from an international collaboration. Hum Pathol. 2023 09; 139:37-46.
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Plasma glycoproteomic biomarkers identify metastatic melanoma patients with reduced clinical benefit from immune checkpoint inhibitor therapy. Front Immunol. 2023; 14:1187332.