Myelinolysis, Central Pontine
"Myelinolysis, Central Pontine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)
MeSH Number(s)
C10.228.140.163.560
C10.314.500
C18.452.132.560
Concept/Terms
Myelinolysis, Central Pontine- Myelinolysis, Central Pontine
- Pontine Myelinolysis, Central
- Myelinoclasis, Central Pontine
- Central Pontine Myelinoclasis
- Central Pontine Myelinolysis
Extrapontine Myelinolysis- Extrapontine Myelinolysis
- Extrapontine Myelinolyses
- Myelinolyses, Extrapontine
- Myelinolysis, Extrapontine
- Extrapontine Myelinoclasis
- Extrapontine Myelinoclases
- Myelinoclases, Extrapontine
- Myelinoclasis, Extrapontine
Below are MeSH descriptors whose meaning is more general than "Myelinolysis, Central Pontine".
Below are MeSH descriptors whose meaning is more specific than "Myelinolysis, Central Pontine".
This graph shows the total number of publications written about "Myelinolysis, Central Pontine" by people in Harvard Catalyst Profiles by year, and whether "Myelinolysis, Central Pontine" was a major or minor topic of these publication.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
Below are the most recent publications written about "Myelinolysis, Central Pontine" by people in Profiles.
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Extrapontine Myelinolysis in a Child with Salt Intoxication. J Pediatr. 2017 07; 186:207-207.e1.
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Case records of the Massachusetts General Hospital. Case 21-2014. A 68-year-old man with a sudden onset of diplopia. N Engl J Med. 2014 Jul 10; 371(2):162-73.
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Is central pontine myelinolysis a sign of pre-symptomatic neurologic form of Wilson disease? Turk J Gastroenterol. 2012 Aug; 23(4):419-20.
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Best cases from the AFIP: osmotic demyelination syndrome. Radiographics. 2009 May-Jun; 29(3):933-8.
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Reversible extrapontine and central pontine myelinolysis presenting with extrapyramidal features. Mov Disord. 2006 Apr; 21(4):585-6.
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Central pontine myelinolysis manifested by temporary blindness: a possible complication of lithium toxicity. Ann Clin Psychiatry. 2002 Dec; 14(4):247-51.
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Neuropathology of liver transplantation. Clin Neuropathol. 1995 Mar-Apr; 14(2):109-17.