Mutagenesis, Site-Directed
"Mutagenesis, Site-Directed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genetically engineered MUTAGENESIS at a specific site in the DNA molecule that introduces a base substitution, or an insertion or deletion.
Concept/Terms
Mutagenesis, Site-Directed- Mutagenesis, Site-Directed
- Mutagenesis, Site Directed
- Site-Directed Mutagenesis
- Mutageneses, Site-Directed
- Site Directed Mutagenesis
- Site-Directed Mutageneses
- Site-Specific Mutagenesis
- Site Specific Mutagenesis
- Mutagenesis, Site-Specific
- Mutageneses, Site-Specific
- Mutagenesis, Site Specific
- Site-Specific Mutageneses
Oligonucleotide-Directed Mutagenesis- Oligonucleotide-Directed Mutagenesis
- Oligonucleotide Directed Mutagenesis
- Mutagenesis, Oligonucleotide-Directed
- Mutageneses, Oligonucleotide-Directed
- Mutagenesis, Oligonucleotide Directed
- Oligonucleotide-Directed Mutageneses
Below are MeSH descriptors whose meaning is more general than "Mutagenesis, Site-Directed".
Below are MeSH descriptors whose meaning is more specific than "Mutagenesis, Site-Directed".
This graph shows the total number of publications written about "Mutagenesis, Site-Directed" by people in Harvard Catalyst Profiles by year, and whether "Mutagenesis, Site-Directed" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 7 | 50 | 57 |
| 1994 | 5 | 63 | 68 |
| 1995 | 4 | 68 | 72 |
| 1996 | 0 | 87 | 87 |
| 1997 | 4 | 65 | 69 |
| 1998 | 5 | 62 | 67 |
| 1999 | 6 | 69 | 75 |
| 2000 | 4 | 73 | 77 |
| 2001 | 5 | 66 | 71 |
| 2002 | 3 | 76 | 79 |
| 2003 | 4 | 69 | 73 |
| 2004 | 1 | 45 | 46 |
| 2005 | 4 | 55 | 59 |
| 2006 | 0 | 41 | 41 |
| 2007 | 3 | 48 | 51 |
| 2008 | 0 | 32 | 32 |
| 2009 | 7 | 32 | 39 |
| 2010 | 1 | 34 | 35 |
| 2011 | 3 | 21 | 24 |
| 2012 | 0 | 29 | 29 |
| 2013 | 1 | 32 | 33 |
| 2014 | 0 | 26 | 26 |
| 2015 | 0 | 20 | 20 |
| 2016 | 1 | 20 | 21 |
| 2017 | 3 | 11 | 14 |
| 2018 | 1 | 16 | 17 |
| 2019 | 0 | 15 | 15 |
| 2020 | 1 | 13 | 14 |
| 2021 | 0 | 10 | 10 |
| 2022 | 1 | 0 | 1 |
Below are the most recent publications written about "Mutagenesis, Site-Directed" by people in Profiles.
-
Targeted editing and evolution of engineered ribosomes in vivo by filtered editing. Nat Commun. 2022 01 10; 13(1):180.
-
Ig Enhancers Increase RNA Polymerase II Stalling at Somatic Hypermutation Target Sequences. J Immunol. 2022 01 01; 208(1):143-154.
-
Biallelic inheritance in a single Pakistani family with intellectual disability implicates new candidate gene RDH14. Sci Rep. 2021 11 30; 11(1):23113.
-
Roadmap for the use of base editors to decipher drug mechanism of action. PLoS One. 2021; 16(9):e0257537.
-
Modifying TIMER to generate a slow-folding DsRed derivative for optimal use in quickly-dividing bacteria. PLoS Pathog. 2021 07; 17(7):e1009284.
-
Mutagenesis and homology modeling reveal a predicted pocket of lysophosphatidylcholine acyltransferase 2 to catch Acyl-CoA. FASEB J. 2021 06; 35(6):e21501.
-
Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes. Nat Commun. 2021 05 20; 12(1):2960.
-
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates. Nature. 2021 05; 593(7859):429-434.
-
Hematoxylin binds to mutant calreticulin and disrupts its abnormal interaction with thrombopoietin receptor. Blood. 2021 04 08; 137(14):1920-1931.
-
pH-dependent and dynamic interactions of cystatin C with heparan sulfate. Commun Biol. 2021 02 12; 4(1):198.