Muscular Dystrophy, Facioscapulohumeral
"Muscular Dystrophy, Facioscapulohumeral" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autosomal dominant degenerative muscle disease characterized by slowly progressive weakness of the muscles of the face, upper-arm, and shoulder girdle. The onset of symptoms usually occurs in the first or second decade of life. Affected individuals usually present with impairment of upper extremity elevation. This tends to be followed by facial weakness, primarily involving the orbicularis oris and orbicularis oculi muscles. (Neuromuscul Disord 1997;7(1):55-62; Adams et al., Principles of Neurology, 6th ed, p1420)
MeSH Number(s)
C05.651.534.500.400
C10.668.491.175.500.400
C16.320.577.400
Concept/Terms
Muscular Dystrophy, Facioscapulohumeral- Muscular Dystrophy, Facioscapulohumeral
- Dystrophies, Facioscapulohumeral Muscular
- Dystrophy, Facioscapulohumeral Muscular
- Facioscapulohumeral Muscular Dystrophies
- Muscular Dystrophies, Facioscapulohumeral
- Progressive Muscular Dystrophy, Facioscapulohumeral Type
- Facioscapulohumeral Atrophy
- Atrophies, Facioscapulohumeral
- Atrophy, Facioscapulohumeral
- Facioscapulohumeral Atrophies
- Facioscapulohumeral Type Progressive Muscular Dystrophy
- Facioscapulohumeral Muscular Dystrophy
- Landouzy-Dejerine Dystrophy
- Dystrophies, Landouzy-Dejerine
- Dystrophy, Landouzy-Dejerine
- Landouzy Dejerine Dystrophy
- Landouzy-Dejerine Dystrophies
Below are MeSH descriptors whose meaning is more general than "Muscular Dystrophy, Facioscapulohumeral".
Below are MeSH descriptors whose meaning is more specific than "Muscular Dystrophy, Facioscapulohumeral".
This graph shows the total number of publications written about "Muscular Dystrophy, Facioscapulohumeral" by people in Harvard Catalyst Profiles by year, and whether "Muscular Dystrophy, Facioscapulohumeral" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 3 | 0 | 3 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 2 | 0 | 2 |
| 2020 | 3 | 0 | 3 |
| 2022 | 1 | 0 | 1 |
| 2023 | 2 | 0 | 2 |
Below are the most recent publications written about "Muscular Dystrophy, Facioscapulohumeral" by people in Profiles.
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Frequency and type of cancers in myotonic dystrophy: A retrospective cross-sectional study. Muscle Nerve. 2023 08; 68(2):142-148.
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Outcomes of scapulothoracic fusion in patients with facioscapulohumeral dystrophy: a comparison of allograft versus autograft bone grafting. J Shoulder Elbow Surg. 2023 Aug; 32(8):1601-1608.
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Randomized phase 2 study of ACE-083, a muscle-promoting agent, in facioscapulohumeral muscular dystrophy. Muscle Nerve. 2022 07; 66(1):50-62.
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Downstream events initiated by expression of FSHD-associated DUX4: Studies of nucleocytoplasmic transport, ?H2AX accumulation, and Bax/Bak-dependence. Biol Open. 2022 02 15; 11(2).
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Cellular and animal models for facioscapulohumeral muscular dystrophy. Dis Model Mech. 2020 10 28; 13(10).
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Therapeutic Approaches in Facioscapulohumeral Muscular Dystrophy. Trends Mol Med. 2021 02; 27(2):123-137.
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p38a Regulates Expression of DUX4 in a Model of Facioscapulohumeral Muscular Dystrophy. J Pharmacol Exp Ther. 2020 09; 374(3):489-498.
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Transgenic mice expressing tunable levels of DUX4 develop characteristic facioscapulohumeral muscular dystrophy-like pathophysiology ranging in severity. Skelet Muscle. 2020 04 11; 10(1):8.
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Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in facioscapulohumeral muscular dystrophy. Sci Transl Med. 2020 03 25; 12(536).
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Electrical impedance myography: MRI-like data without the need for MRI. Muscle Nerve. 2020 05; 61(5):554-556.