Muscular Dystrophy, Duchenne
"Muscular Dystrophy, Duchenne" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
MeSH Number(s)
C05.651.534.500.300
C10.668.491.175.500.300
C16.320.322.562
C16.320.577.300
Concept/Terms
Muscular Dystrophy, Duchenne- Muscular Dystrophy, Duchenne
- Childhood Pseudohypertrophic Muscular Dystrophy
- Duchenne Muscular Dystrophy
- Dystrophy, Duchenne Muscular
- Duchenne-Type Progressive Muscular Dystrophy
- Duchenne Type Progressive Muscular Dystrophy
- Muscular Dystrophy, Pseudohypertrophic Progressive, Duchenne Type
- Muscular Dystrophy, Pseudohypertrophic
- Dystrophies, Pseudohypertrophic Muscular
- Dystrophy, Pseudohypertrophic Muscular
- Muscular Dystrophies, Pseudohypertrophic
- Pseudohypertrophic Muscular Dystrophies
- Pseudohypertrophic Muscular Dystrophy
- Muscular Dystrophy, Pseudohypertrophic, Childhood
- Progressive Muscular Dystrophy, Duchenne Type
- Pseudohypertrophic Childhood Muscular Dystrophy
- Pseudohypertrophic Muscular Dystrophy, Childhood
- Childhood Muscular Dystrophy, Pseudohypertrophic
- Muscular Dystrophy, Childhood, Pseudohypertrophic
Below are MeSH descriptors whose meaning is more general than "Muscular Dystrophy, Duchenne".
- Diseases [C]
- Musculoskeletal Diseases [C05]
- Muscular Diseases [C05.651]
- Muscular Disorders, Atrophic [C05.651.534]
- Muscular Dystrophies [C05.651.534.500]
- Muscular Dystrophy, Duchenne [C05.651.534.500.300]
- Nervous System Diseases [C10]
- Neuromuscular Diseases [C10.668]
- Muscular Diseases [C10.668.491]
- Muscular Disorders, Atrophic [C10.668.491.175]
- Muscular Dystrophies [C10.668.491.175.500]
- Muscular Dystrophy, Duchenne [C10.668.491.175.500.300]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Genetic Diseases, X-Linked [C16.320.322]
- Muscular Dystrophy, Duchenne [C16.320.322.562]
- Muscular Dystrophies [C16.320.577]
- Muscular Dystrophy, Duchenne [C16.320.577.300]
Below are MeSH descriptors whose meaning is more specific than "Muscular Dystrophy, Duchenne".
This graph shows the total number of publications written about "Muscular Dystrophy, Duchenne" by people in Harvard Catalyst Profiles by year, and whether "Muscular Dystrophy, Duchenne" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 1 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 3 | 2 | 5 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 3 | 3 |
| 2005 | 5 | 0 | 5 |
| 2006 | 4 | 1 | 5 |
| 2007 | 6 | 0 | 6 |
| 2008 | 3 | 1 | 4 |
| 2009 | 3 | 2 | 5 |
| 2010 | 5 | 0 | 5 |
| 2011 | 5 | 1 | 6 |
| 2012 | 1 | 1 | 2 |
| 2013 | 7 | 2 | 9 |
| 2014 | 10 | 3 | 13 |
| 2015 | 7 | 1 | 8 |
| 2016 | 8 | 1 | 9 |
| 2017 | 11 | 2 | 13 |
| 2018 | 11 | 1 | 12 |
| 2019 | 11 | 3 | 14 |
| 2020 | 11 | 1 | 12 |
| 2021 | 9 | 2 | 11 |
| 2022 | 11 | 0 | 11 |
Below are the most recent publications written about "Muscular Dystrophy, Duchenne" by people in Profiles.
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Tandem duplication within the DMD gene in Labrador retrievers with a mild clinical phenotype. Neuromuscul Disord. 2022 10; 32(10):836-841.
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Comparison of Quantitative Ultrasound Methods to Classify Dystrophic and Obese Models of Skeletal Muscle. Ultrasound Med Biol. 2022 09; 48(9):1918-1932.
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Diagnostic capabilities of nanopore long-read sequencing in muscular dystrophy. Ann Clin Transl Neurol. 2022 08; 9(8):1302-1309.
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Effect of Different Corticosteroid Dosing Regimens on Clinical Outcomes in Boys With Duchenne Muscular Dystrophy: A Randomized Clinical Trial. JAMA. 2022 04 19; 327(15):1456-1468.
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Hybrid management of dysphagia lusoria in a boy with Duchenne's muscular dystrophy. Cardiol Young. 2022 Nov; 32(11):1842-1844.
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Beneficial impacts of neuromuscular electrical stimulation on muscle structure and function in the zebrafish model of Duchenne muscular dystrophy. Elife. 2022 03 24; 11.
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Intron mutations and early transcription termination in Duchenne and Becker muscular dystrophy. Hum Mutat. 2022 04; 43(4):511-528.
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Sarcospan increases laminin-binding capacity of a-dystroglycan to ameliorate DMD independent of Galgt2. Hum Mol Genet. 2022 03 03; 31(5):718-732.
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Investigating the role of dystrophin isoform deficiency in motor function in Duchenne muscular dystrophy. J Cachexia Sarcopenia Muscle. 2022 04; 13(2):1360-1372.
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Current Practices in Treating Cardiomyopathy and Heart Failure in Duchenne Muscular Dystrophy (DMD): Understanding Care Practices in Order to Optimize DMD Heart Failure Through ACTION. Pediatr Cardiol. 2022 Jun; 43(5):977-985.