Muscular Dystrophies, Limb-Girdle
"Muscular Dystrophies, Limb-Girdle" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterogenous group of inherited muscular dystrophy that can be autosomal dominant or autosomal recessive. There are many forms (called LGMDs) involving genes encoding muscle membrane proteins such as the sarcoglycan (SARCOGLYCANS) complex that interacts with DYSTROPHIN. The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the HIPS and SHOULDERS (the pelvic and shoulder girdles).
MeSH Number(s)
C05.651.534.500.280
C10.668.491.175.500.149
C16.320.577.280
Concept/Terms
Muscular Dystrophies, Limb-Girdle- Muscular Dystrophies, Limb-Girdle
- Muscular Dystrophies, Limb Girdle
- Limb-Girdle Muscular Dystrophies
- Limb Girdle Muscular Dystrophies
- Limb-Girdle Muscular Dystrophy
- Limb Girdle Muscular Dystrophy
- Muscular Dystrophy, Limb-Girdle
- Muscular Dystrophy, Limb Girdle
Below are MeSH descriptors whose meaning is more general than "Muscular Dystrophies, Limb-Girdle".
Below are MeSH descriptors whose meaning is more specific than "Muscular Dystrophies, Limb-Girdle".
This graph shows the total number of publications written about "Muscular Dystrophies, Limb-Girdle" by people in Harvard Catalyst Profiles by year, and whether "Muscular Dystrophies, Limb-Girdle" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 5 | 0 | 5 |
| 2015 | 3 | 0 | 3 |
| 2016 | 2 | 0 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 2 | 0 | 2 |
| 2020 | 2 | 0 | 2 |
| 2021 | 2 | 0 | 2 |
| 2022 | 2 | 0 | 2 |
Below are the most recent publications written about "Muscular Dystrophies, Limb-Girdle" by people in Profiles.
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2022 HRS expert consensus statement on evaluation and management of arrhythmic risk in neuromuscular disorders. Heart Rhythm. 2022 10; 19(10):e61-e120.
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Evaluating Therapeutic Activity of Galectin-1 in Sarcolemma Repair of Skeletal Muscle. Methods Mol Biol. 2022; 2442:663-683.
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Therapeutic Benefit of Galectin-1: Beyond Membrane Repair, a Multifaceted Approach to LGMD2B. Cells. 2021 11 17; 10(11).
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The birth of informed decisions: Pregnancy and muscular dystrophy. Muscle Nerve. 2021 06; 63(6):787-789.
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Treatment with galectin-1 improves myogenic potential and membrane repair in dysferlin-deficient models. PLoS One. 2020; 15(9):e0238441.
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A Molecular Diagnosis of LGMDR1 Established by RNA Sequencing. Can J Neurol Sci. 2021 03; 48(2):293-296.
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The genetic profile of dysferlinopathy in a cohort of 209 cases: Genotype-phenotype relationship and a hotspot on the inner DysF domain. Hum Mutat. 2020 09; 41(9):1540-1554.
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Sequential targeted exome sequencing of 1001 patients affected by unexplained limb-girdle weakness. Genet Med. 2020 09; 22(9):1478-1488.
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AMPK Complex Activation Promotes Sarcolemmal Repair in Dysferlinopathy. Mol Ther. 2020 04 08; 28(4):1133-1153.
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Identification of a Novel Deep Intronic Mutation in CAPN3 Presenting a Promising Target for Therapeutic Splice Modulation. J Neuromuscul Dis. 2019; 6(4):475-483.