Harvard Catalyst Profiles

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Multiple Endocrine Neoplasia Type 2a

"Multiple Endocrine Neoplasia Type 2a" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A form of multiple endocrine neoplasia characterized by the presence of medullary carcinoma (CARCINOMA, MEDULLARY) of the THYROID GLAND, and usually with the co-occurrence of PHEOCHROMOCYTOMA, producing CALCITONIN and ADRENALINE, respectively. Less frequently, it can occur with hyperplasia or adenoma of the PARATHYROID GLANDS. This disease is due to gain-of-function mutations of the MEN2 gene on CHROMOSOME 10 (Locus: 10q11.2), also known as the RET proto-oncogene that encodes a RECEPTOR PROTEIN-TYROSINE KINASE. It is an autosomal dominant inherited disease.


This graph shows the total number of publications written about "Multiple Endocrine Neoplasia Type 2a" by people in Harvard Catalyst Profiles by year, and whether "Multiple Endocrine Neoplasia Type 2a" was a major or minor topic of these publication.
Bar chart showing 24 publications over 15 distinct years, with a maximum of 3 publications in 1999 and 2002
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.