Microscopy, Fluorescence, Multiphoton
"Microscopy, Fluorescence, Multiphoton" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Fluorescence microscopy utilizing multiple low-energy photons to produce the excitation event of the fluorophore. Multiphoton microscopes have a simplified optical path in the emission side due to the lack of an emission pinhole, which is necessary with normal confocal microscopes. Ultimately this allows spatial isolation of the excitation event, enabling deeper imaging into optically thick tissue, while restricting photobleaching and phototoxicity to the area being imaged.
MeSH Number(s)
E01.370.350.515.458.500
E05.595.458.500
Below are MeSH descriptors whose meaning is more general than "Microscopy, Fluorescence, Multiphoton".
Below are MeSH descriptors whose meaning is more specific than "Microscopy, Fluorescence, Multiphoton".
This graph shows the total number of publications written about "Microscopy, Fluorescence, Multiphoton" by people in Harvard Catalyst Profiles by year, and whether "Microscopy, Fluorescence, Multiphoton" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2003 | 6 | 2 | 8 |
| 2004 | 0 | 3 | 3 |
| 2005 | 2 | 1 | 3 |
| 2006 | 1 | 2 | 3 |
| 2007 | 9 | 4 | 13 |
| 2008 | 6 | 4 | 10 |
| 2009 | 8 | 4 | 12 |
| 2010 | 3 | 5 | 8 |
| 2011 | 5 | 5 | 10 |
| 2012 | 3 | 2 | 5 |
| 2013 | 4 | 7 | 11 |
| 2014 | 3 | 6 | 9 |
| 2015 | 6 | 9 | 15 |
| 2016 | 3 | 8 | 11 |
| 2017 | 2 | 6 | 8 |
| 2018 | 4 | 4 | 8 |
| 2019 | 5 | 2 | 7 |
| 2020 | 1 | 3 | 4 |
| 2021 | 3 | 2 | 5 |
| 2022 | 2 | 1 | 3 |
| 2023 | 1 | 0 | 1 |
Below are the most recent publications written about "Microscopy, Fluorescence, Multiphoton" by people in Profiles.
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Tutorial: multiphoton microscopy to advance neuroscience research. Methods Appl Fluoresc. 2023 Feb 22; 11(1).
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Label-free analysis of inflammatory tissue remodeling in murine lung tissue based on multiphoton microscopy, Raman spectroscopy and machine learning. J Biophotonics. 2022 09; 15(9):e202200073.
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Multiphoton microscopy for label-free multicolor imaging of peripheral nerve. J Biomed Opt. 2022 05; 27(5).
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Intravital Microscopy in Atherosclerosis Research. Methods Mol Biol. 2022; 2419:645-658.
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Role of the Phospholipase C Pathway and Calcium Mobilization in Oxytocin-Induced Contraction of Lacrimal Gland Myoepithelial Cells. Invest Ophthalmol Vis Sci. 2021 11 01; 62(14):25.
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Two-photon excitation fluorescent spectral and decay properties of retrograde neuronal tracer Fluoro-Gold. Sci Rep. 2021 09 10; 11(1):18053.
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Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences. Nat Commun. 2021 05 27; 12(1):3190.
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In vivo brain imaging of mitochondrial Ca2+ in neurodegenerative diseases with multiphoton microscopy. Biochim Biophys Acta Mol Cell Res. 2021 05; 1868(6):118998.
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Quantitative evaluation of the human vocal fold extracellular matrix using multiphoton microscopy and optical coherence tomography. Sci Rep. 2021 01 28; 11(1):2440.
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Three-photon imaging of synthetic dyes in deep layers of the neocortex. Sci Rep. 2020 10 01; 10(1):16351.