Micronuclei, Chromosome-Defective
"Micronuclei, Chromosome-Defective" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Defective nuclei produced during the TELOPHASE of MITOSIS or MEIOSIS by lagging CHROMOSOMES or chromosome fragments derived from spontaneous or experimentally induced chromosomal structural changes.
MeSH Number(s)
A11.284.430.106.570
A11.284.430.214.190.875.117.570
C23.550.210.570
G05.365.590.175.570
Concept/Terms
Micronuclei, Chromosome-Defective- Micronuclei, Chromosome-Defective
- Chromosome-Defective Micronucleus
- Micronuclei, Chromosome Defective
- Micronucleus, Chromosome-Defective
- Micronucleus, Chromosome Defective
- Chromosome-Defective Micronuclei
- Chromosome Defective Micronuclei
Micronuclei, Genotoxicant-Induced- Micronuclei, Genotoxicant-Induced
- Genotoxicant-Induced Micronucleus
- Micronuclei, Genotoxicant Induced
- Micronucleus, Genotoxicant-Induced
- Genotoxicant-Induced Micronuclei
- Genotoxicant Induced Micronuclei
Below are MeSH descriptors whose meaning is more general than "Micronuclei, Chromosome-Defective".
Below are MeSH descriptors whose meaning is more specific than "Micronuclei, Chromosome-Defective".
This graph shows the total number of publications written about "Micronuclei, Chromosome-Defective" by people in Harvard Catalyst Profiles by year, and whether "Micronuclei, Chromosome-Defective" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 1 | 3 |
| 2020 | 1 | 0 | 1 |
Below are the most recent publications written about "Micronuclei, Chromosome-Defective" by people in Profiles.
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Development of reconstructed intestinal micronucleus cytome (RICyt) assay in 3D human gut model for genotoxicity assessment of orally ingested substances. Arch Toxicol. 2022 05; 96(5):1455-1471.
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Small but mighty: the causes and consequences of micronucleus rupture. Exp Mol Med. 2020 11; 52(11):1777-1786.
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Role of apurinic/apyrimidinic nucleases in the regulation of homologous recombination in myeloma: mechanisms and translational significance. Blood Cancer J. 2018 09 25; 8(10):92.
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A meta-analysis of epidemiologic studies of occupationally exposed styrene workers and micronuclei levels. Mutat Res Genet Toxicol Environ Mutagen. 2019 Jan; 837:15-28.
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Nuclear envelope assembly defects link mitotic errors to chromothripsis. Nature. 2018 09; 561(7724):551-555.
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SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma. Cancer Res. 2018 06 15; 78(12):3135-3146.
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Is inflammatory micronucleation the key to a successful anti-mitotic cancer drug? Open Biol. 2017 11; 7(11).
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Photodynamic therapy combined to cisplatin potentiates cell death responses of cervical cancer cells. BMC Cancer. 2017 02 10; 17(1):123.
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Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining. Nat Cell Biol. 2017 Jan; 19(1):68-75.
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Chromothripsis: A New Mechanism for Rapid Karyotype Evolution. Annu Rev Genet. 2015; 49:183-211.